[HTML][HTML] Cerebrospinal fluid dynamics and intracranial pressure elevation in neurological diseases
SW Bothwell, D Janigro, A Patabendige - Fluids and Barriers of the CNS, 2019 - Springer
The fine balance between the secretion, composition, volume and turnover of cerebrospinal
fluid (CSF) is strictly regulated. However, during certain neurological diseases, this balance …
fluid (CSF) is strictly regulated. However, during certain neurological diseases, this balance …
[HTML][HTML] Choroid plexus aquaporins in CSF homeostasis and the glymphatic system: Their relevance for Alzheimer's disease
C Municio, L Carrero, D Antequera, E Carro - International Journal of …, 2023 - mdpi.com
The glymphatic system, a fluid-clearance pathway involved in brain waste clearance, is
known to be impaired in neurological disorders, including Alzheimer's disease (AD). For this …
known to be impaired in neurological disorders, including Alzheimer's disease (AD). For this …
Loss of aquaporin-4 results in glymphatic system dysfunction via brain-wide interstitial fluid stagnation
The glymphatic system is a fluid transport network of cerebrospinal fluid (CSF) entering the
brain along arterial perivascular spaces, exchanging with interstitial fluid (ISF), ultimately …
brain along arterial perivascular spaces, exchanging with interstitial fluid (ISF), ultimately …
A clinical primer for the glymphatic system
LP Carlstrom, A Eltanahy, A Perry, AA Rabinstein… - Brain, 2022 - academic.oup.com
The complex and dynamic system of fluid flow through the perivascular and interstitial
spaces of the CNS has new-found implications for neurological diseases. CSF movement …
spaces of the CNS has new-found implications for neurological diseases. CSF movement …
Delayed clearance of cerebrospinal fluid tracer from choroid plexus in idiopathic normal pressure hydrocephalus
PK Eide, LM Valnes, AH Pripp… - Journal of Cerebral …, 2020 - journals.sagepub.com
Impaired clearance of amyloid-β from choroid plexus is one proposed mechanism behind
amyloid deposition in Alzheimer's disease. The present study examined whether clearance …
amyloid deposition in Alzheimer's disease. The present study examined whether clearance …
The impact of hypoxia on blood-brain, blood-CSF, and CSF-brain barriers
The blood-brain barrier (BBB), blood-cerebrospinal fluid (CSF) barrier (BCSFB), and CSF-
brain barriers (CSFBB) are highly regulated barriers in the central nervous system …
brain barriers (CSFBB) are highly regulated barriers in the central nervous system …
[HTML][HTML] AQP1 and AQP4 contribution to cerebrospinal fluid homeostasis
JL Trillo-Contreras, JJ Toledo-Aral, M Echevarría… - Cells, 2019 - mdpi.com
Aquaporin 1 (AQP1), expressed in epithelial cells of the choroid plexus, and aquaporin 4
(AQP4) present in ependymal cells and glia limitants have been proposed to play a …
(AQP4) present in ependymal cells and glia limitants have been proposed to play a …
[HTML][HTML] Why is delirium more frequent in the elderly?
O Bugiani - Neurological Sciences, 2021 - Springer
An aging-related reduction in the brain's functional reserve may explain why delirium is
more frequent in the elderly than in younger people insofar as the reserve becomes …
more frequent in the elderly than in younger people insofar as the reserve becomes …
[HTML][HTML] Cellular distribution of brain aquaporins and their contribution to cerebrospinal fluid homeostasis and hydrocephalus
JL Trillo-Contreras, R Ramírez-Lorca, J Villadiego… - Biomolecules, 2022 - mdpi.com
Brain aquaporins facilitate the movement of water between the four water compartments:
blood, cerebrospinal fluid, interstitial fluid, and intracellular fluid. This work analyzes the …
blood, cerebrospinal fluid, interstitial fluid, and intracellular fluid. This work analyzes the …
Regulation of aquaporin‐4 expression in the central nervous system investigated using M23‐AQP4 null mouse
In astrocytes, unknown mechanisms regulate the expression of M1 and M23 isoforms of
water channel aquaporin‐4 (M1‐AQP4 and M23‐AQP4). The ratio between these two …
water channel aquaporin‐4 (M1‐AQP4 and M23‐AQP4). The ratio between these two …