New developments in CRISPR/Cas-based functional genomics and their implications for research using zebrafish
SV Prykhozhij, L Caceres, JN Berman - Current gene therapy, 2017 - ingentaconnect.com
Introduction: Genome editing using CRISPR/Cas9 has advanced very rapidly in its scope,
versatility and ease of use. Zebrafish (Danio rerio) has been one of the vertebrate model …
versatility and ease of use. Zebrafish (Danio rerio) has been one of the vertebrate model …
Defects of the glycinergic synapse in zebrafish
K Ogino, H Hirata - Frontiers in molecular neuroscience, 2016 - frontiersin.org
Glycine mediates fast inhibitory synaptic transmission. Physiological importance of the
glycinergic synapse is well established in the brainstem and the spinal cord. In humans, the …
glycinergic synapse is well established in the brainstem and the spinal cord. In humans, the …
A Novel Dietary Source of EPA and DHA: Metabolic Engineering of an Important Freshwater Species—Common Carp by fat1-Transgenesis
X Zhang, S Pang, C Liu, H Wang, D Ye, Z Zhu… - Marine Biotechnology, 2019 - Springer
Omega-3 polyunsaturated fatty acids (n-3 PUFAs), such as eicosapentaenoic acid (20: 5n-3,
EPA) and docosahexaenoic acid (22: 6n-3, DHA), are essential for neural development and …
EPA) and docosahexaenoic acid (22: 6n-3, DHA), are essential for neural development and …
Tendon cell regeneration is mediated by attachment site-resident progenitors and BMP signaling
The musculoskeletal system is a striking example of how cell identity and position is
coordinated across multiple tissues to ensure function. However, it is unclear upon tissue …
coordinated across multiple tissues to ensure function. However, it is unclear upon tissue …
Optimising the zebrafish Cre/Lox toolbox. Codon improved iCre, new gateway tools, Cre protein and guidelines
We recently introduced the Cre/Lox technology in our laboratory for both transient (mRNA
injections) and stable/transgenic experiments. We experienced significant issues such as …
injections) and stable/transgenic experiments. We experienced significant issues such as …
Oligodendrocyte Development in the Absence of Their Target Axons In Vivo
Oligodendrocytes form myelin around axons of the central nervous system, enabling
saltatory conduction. Recent work has established that axons can regulate certain aspects of …
saltatory conduction. Recent work has established that axons can regulate certain aspects of …
Transsynaptic labeling and transcriptional control of zebrafish neural circuits
Deciphering the connectome, the ensemble of synaptic connections that underlie brain
function, is a central goal of neuroscience research. The trans-Tango genetic approach …
function, is a central goal of neuroscience research. The trans-Tango genetic approach …
Transcriptional regulation using the Q system in transgenic zebrafish
A Ghosh, ME Halpern - Methods in cell biology, 2016 - Elsevier
Methods to label cell populations selectively or to modify their gene expression are critical
tools in the study of developmental or physiological processes in vivo. A variety of …
tools in the study of developmental or physiological processes in vivo. A variety of …
Triclosan Affects Ca2+ Regulatory Module and Musculature Development in Skeletal Myocyte during Early Life Stages of Zebrafish (Danio rerio)
Z Ma, H Liu, H Yu - Environmental Science & Technology, 2019 - ACS Publications
Advanced technologies for toxicity tests are designed to identify biomarkers with superior
predictive power or end points of the complex web of biological pathways. However, the …
predictive power or end points of the complex web of biological pathways. However, the …
An enhanced hTERT promoter-driven CRISPR/Cas9 system selectively inhibits the progression of bladder cancer cells
X Huang, C Zhuang, C Zhuang, T Xiong, Y Li… - Molecular …, 2017 - pubs.rsc.org
The current therapies for treating tumors are lacking in efficacy and specificity. Synthetic
biology principles may bring some new possible methods for curing cancer. Here we …
biology principles may bring some new possible methods for curing cancer. Here we …