Cerebrovascular reactivity (CVR) is an indicator of cerebrovascular reserve and provides
important information about vascular health in a range of brain conditions and diseases …

Functional magnetic resonance imaging (fMRI) is a methodology for detecting dynamic
patterns of activity in the working human brain. Although the initial discoveries that led to …

Cerebrovascular reactivity (CVR) is defined as the ability of vessels to alter their caliber in
response to vasoactive factors, by means of dilating or constricting, in order to increase or …

In the rodent brain the hemodynamic response to a brief external stimulus changes
significantly during development. Analogous changes in human infants would complicate …

The human brain constitutes 2% of the body's total mass but uses 20% of the oxygen. The
rate of the brain's oxygen utilization can be derived from a knowledge of cerebral blood flow …

Functional magnetic resonance imaging (fMRI) using the blood oxygenation level-
dependent (BOLD) contrast indirectly probes neuronal activity changes via evoked cerebral …

Blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI)
is most commonly used in a semi-quantitative manner to infer changes in brain activity …

Stimulation of cerebral vasculature using hypercapnia has been widely used to study
cerebral vascular reactivity (CVR), which can be expressed as the quantitative change in …

We present a method allowing determination of resting cerebral oxygen metabolism
(CMRO2) from MRI and end-tidal O2 measurements acquired during a pair of respiratory …

White matter (WM) comprises about half of the brain and its dysfunction is implicated in
many brain disorders. While structural properties in healthy and diseased WM have been …