[HTML][HTML] How vascular smooth muscle cell phenotype switching contributes to vascular disease

G Cao, X Xuan, J Hu, R Zhang, H Jin… - Cell Communication and …, 2022 - Springer
Vascular smooth muscle cells (VSMCs) are the most abundant cell in vessels. Earlier
experiments have found that VSMCs possess high plasticity. Vascular injury stimulates …

Meta-analysis of individual patient data to examine factors affecting growth and rupture of small abdominal aortic aneurysms

MJ Sweeting, SG Thompson, LC Brown… - Journal of British …, 2012 - academic.oup.com
Background Surveillance is a common management strategy for small abdominal aortic
aneurysm (AAA)(3· 0–5· 4 cm in diameter). Individual characteristics, other than diameter …

[HTML][HTML] Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target

T Roychowdhury, D Klarin, MG Levin, JM Spin… - Nature …, 2023 - nature.com
Abdominal aortic aneurysm (AAA) is a common disease with substantial heritability. In this
study, we performed a genome-wide association meta-analysis from 14 discovery cohorts …

[HTML][HTML] The Society for Vascular Surgery practice guidelines on the care of patients with an abdominal aortic aneurysm

EL Chaikof, RL Dalman, MK Eskandari… - Journal of vascular …, 2018 - Elsevier
Background Decision-making related to the care of patients with an abdominal aortic
aneurysm (AAA) is complex. Aneurysms present with varying risks of rupture, and patient …

[HTML][HTML] The care of patients with an abdominal aortic aneurysm: the Society for Vascular Surgery practice guidelines

EL Chaikof, DC Brewster, RL Dalman… - Journal of vascular …, 2009 - jvascsurg.org
The Clinical Practice Council of the Society for Vascular Surgery charged a writing
committee with the task of updating practice guidelines, initally published in 2003, for …

Statins reduce abdominal aortic aneurysm growth, rupture, and perioperative mortality: a systematic review and meta‐analysis

K Salata, M Syed, MA Hussain… - Journal of the …, 2018 - Am Heart Assoc
Background There are no recognized pharmacological treatments for abdominal aortic
aneurysms (AAA), although statins are suggested to be beneficial. We sought to summarize …

[HTML][HTML] Abdominal aortic aneurysm

B Keisler, C Carter - American family physician, 2015 - aafp.org
Abdominal aortic aneurysm refers to abdominal aortic dilation of 3.0 cm or greater. The main
risk factors are age older than 65 years, male sex, and smoking history. Other risk factors …

[HTML][HTML] Metformin treatment status and abdominal aortic aneurysm disease progression

N Fujimura, J Xiong, EB Kettler, H Xuan… - Journal of vascular …, 2016 - Elsevier
Objective In population-based studies performed on multiple continents during the past two
decades, diabetes mellitus has been negatively associated with the prevalence and …

JCS/JSCVS/JATS/JSVS 2020 guideline on diagnosis and treatment of aortic aneurysm and aortic dissection

H Ogino, O Iida, K Akutsu, Y Chiba, H Hayashi… - Circulation …, 2023 - jstage.jst.go.jp
Of the clinical practice guideline of the Japanese Circulation Society concerning aortic
diseases, the Guidelines on Diagnosis and Treatment of Aortic Dissection (first edition) were …

Cardiovascular effects of statins, beyond lipid-lowering properties

CG Mihos, AM Pineda, O Santana - Pharmacological research, 2014 - Elsevier
Abstract The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, better known as
'statins', are amongst the most widely used medications in the world. They have become a …