[HTML][HTML] Novel pharmacological approaches in abdominal aortic aneurysm

L Puertas-Umbert, R Almendra-Pegueros… - Clinical …, 2023 - portlandpress.com
Abdominal aortic aneurysm (AAA) is a severe vascular disease and a major public health
issue with an unmet medical need for therapy. This disease is featured by a progressive …

Pharmacological therapy of abdominal aortic aneurysm: an update

Y Wang, Z Liu, J Ren, M Xiang - Current vascular …, 2018 - ingentaconnect.com
Background: Abdominal aortic aneurysm (AAA), a progressive segmental abdominal aortic
dilation, is associated with high mortality. AAA is characterized by inflammation, smooth …

[HTML][HTML] Effects of statin therapy on abdominal aortic aneurysm growth: a meta-analysis and meta-regression of observational comparative studies

H Takagi, H Yamamoto, K Iwata, S Goto… - European Journal of …, 2012 - Elsevier
OBJECTIVE: To determine whether statin therapy reduces the growth rate of small
abdominal aortic aneurysms (AAAs). DESIGN: A meta-analysis and a meta-regression of …

Perioperative statin therapy for improving outcomes during and after noncardiac vascular surgery

RD Sanders, A Nicholson, SR Lewis… - Cochrane Database …, 2013 - cochranelibrary.com
Background Patients undergoing vascular surgery are a high‐risk population with
widespread atherosclerosis, an adverse cardiovascular risk profile and often multiple co …

[HTML][HTML] Hyperlipidemia: drugs for cardiovascular risk reduction in adults

AR Last, JD Ference, ER Menzel - American family physician, 2017 - aafp.org
Guidelines from the American College of Cardiology/American Heart Association
(ACC/AHA) and the UK National Institute for Health and Care Excellence (NICE) indicate …

Current status of medical treatment for abdominal aortic aneurysm

K Kurosawa, JS Matsumura, D Yamanouchi - Circulation Journal, 2013 - jstage.jst.go.jp
2861 Medical Treatment for Abdominal Aortic Aneurysm ical treatments include anti-
hypertensives, statins, and antibiotics, some of which might work as MMP inhibitors. Tables …

[HTML][HTML] Statin therapy is associated with improved survival after endovascular and open aneurysm repair

JL de Bruin, AF Baas, MW Heymans, MG Buimer… - Journal of vascular …, 2014 - Elsevier
Background The relationship between numerous risk factors and perioperative mortality
after cardiovascular surgery has been studied extensively. While improved perioperative …

Opportunities in abdominal aortic aneurysm research: epidemiology, genetics, and pathophysiology

H Kuivaniemi, JR Elmore - Annals of vascular surgery, 2012 - Elsevier
Aortic aneurysms are a complex genetic disorder with known environmental risk factors such
as smoking. Along the length of the aorta, significant heterogeneity occurs in the distribution …

[HTML][HTML] Efficacy and mechanism of angiotensin II receptor blocker treatment in experimental abdominal aortic aneurysms

Y Iida, B Xu, GM Schultz, V Chow, JJ White… - PloS one, 2012 - journals.plos.org
Background Despite the importance of the renin-angiotensin (Ang) system in abdominal
aortic aneurysm (AAA) pathogenesis, strategies targeting this system to prevent clinical …

[HTML][HTML] Outcomes of endovascular abdominal aortic aneurysm repair in high-risk patients

S Lim, PM Halandras, T Park, Y Lee… - Journal of vascular …, 2015 - Elsevier
Objective Although the endovascular aneurysm repair trial 2 (EVAR-2) demonstrated no
benefit of EVAR in high-risk (HR) patients, EVAR is still performed widely in this patient …