Identifying genetic determinants of Streptococcus pyogenes-host interactions in a murine intact skin infection model

RV Wilkening, C Langouët-Astrié, MM Severn… - Cell reports, 2023 - cell.com
Streptococcus pyogenes is an obligate human pathobiont associated with many disease
states. Here, we present a model of S. pyogenes infection using intact murine epithelium …

[HTML][HTML] Secreted virulence factors of Streptococcus pyogenes

T Barnett, A Indraratna… - … pyogenes: Basic Biology …, 2022 - ncbi.nlm.nih.gov
Streptococcus pyogenes strains produce a wide variety of secreted or released extracellular
products, many of which are virulence factors due to their roles in promoting disease and/or …

Cooperation of quorum sensing and central carbon metabolism in the pathogenesis of Gram-positive bacteria

S Gao, Y Wang, S Yuan, J Zuo, W Jin, Y Shen… - Microbiological …, 2024 - Elsevier
Quorum sensing (QS), an integral component of bacterial communication, is essential in
coordinating the collective response of diverse bacterial pathogens. Central carbon …

Identification and characterization of negative regulators of rgg1518 quorum sensing in streptococcus pneumoniae

D Hu, I Laczkovich, MJ Federle… - Journal of …, 2023 - Am Soc Microbiol
Streptococcus pneumoniae is an agent of otitis media, septicemia, and meningitis and
remains the leading cause of community-acquired pneumonia regardless of vaccine use. Of …

The proteomic and transcriptomic landscapes altered by Rgg2/3 activity in Streptococcus pyogenes

BE Rued, CM Anderson, MJ Federle - Journal of Bacteriology, 2022 - Am Soc Microbiol
Streptococcus pyogenes, otherwise known as Group A Streptococcus (GAS), is an important
and highly adaptable human pathogen with the ability to cause both superficial and severe …

A Streptomyces tendae Specialized Metabolite Inhibits Quorum Sensing in Group A Streptococcus

VM Nepomuceno, KM Tylor, S Carlson… - Microbiology …, 2023 - Am Soc Microbiol
Quorum sensing (QS) is a means of bacterial communication accomplished by microbe-
produced signals and sensory systems. QS systems regulate important population-wide …

Rgg2/Rgg3 quorum sensing is a determinant of Streptococcus pyogenes-host interactions in a murine intact skin infection model

RV Wilkening, C Langouët-Astrié, M Severn… - bioRxiv, 2023 - biorxiv.org
Streptococcus pyogenes is an obligate human pathobiont associated with many disease
states. Here, we present a novel model of S. pyogenes infection using intact murine …

Streptococcus pneumoniae Rgg/SHP Quorum-sensing Networks and Upstream Regulators of Rgg/SHP1518

D Hu - 2022 - search.proquest.com
In bacteria, quorum-sensing (QS) is a mechanism by which neighboring cells communicate
via secreted signaling molecules to regulate cell behaviors. In Streptococcus pneumoniae …