Overview of the 2022 WHO classification of adrenal cortical tumors

O Mete, LA Erickson, CC Juhlin, RR de Krijger… - Endocrine …, 2022 - Springer
The new WHO classification of adrenal cortical proliferations reflects translational advances
in the fields of endocrine pathology, oncology and molecular biology. By adopting a …

Advances in translational research of the rare cancer type adrenocortical carcinoma

C Ghosh, J Hu, E Kebebew - Nature Reviews Cancer, 2023 - nature.com
Adrenocortical carcinoma is a rare malignancy with an annual worldwide incidence of 1–2
cases per 1 million and a 5-year survival rate of< 60%. Although adrenocortical carcinoma is …

KDM1A inactivation causes hereditary food-dependent Cushing syndrome

A Vaczlavik, L Bouys, F Violon, G Giannone… - Genetics in …, 2022 - Elsevier
Purpose This study aimed to investigate the genetic cause of food-dependent Cushing
syndrome (FDCS) observed in patients with primary bilateral macronodular adrenal …

Prognostic utility of the Ki-67 labeling index in follicular thyroid tumors: a 20-year experience from a tertiary thyroid center

LS Hellgren, A Stenman, JO Paulsson, A Höög… - Endocrine …, 2022 - Springer
Follicular thyroid tumors pose a diagnostic challenge on the preoperative level, as the
discrimination between follicular thyroid carcinoma (FTC) and adenoma (FTA) demands …

Histopathologic features of adrenal cortical carcinoma

A Gambella, M Volante, M Papotti - Advances in Anatomic …, 2023 - journals.lww.com
Adrenal cortical carcinoma (ACC) is a rare and aggressive malignancy that poses
challenging issues regarding the diagnostic workup. Indeed, no presurgical technique or …

Second-generation neuroendocrine immunohistochemical markers: reflections from clinical implementation

CC Juhlin - Biology, 2021 - mdpi.com
Simple Summary Neuroendocrine tumors are a collection of neoplastic lesions arising in
cells with traits similar to hormone-producing and nerve cells with the ability to secrete …

On the chopping block: overview of DICER1 mutations in endocrine and neuroendocrine neoplasms

CC Juhlin - Surgical Pathology Clinics, 2023 - surgpath.theclinics.com
Mutational inactivation of the DICER1 gene causes aberrant micro-RNA maturation, which in
turn may have consequences for the posttranscriptional regulation of gene expression …

Advances in adrenal and extra-adrenal paraganglioma: practical synopsis for pathologists

CC Juhlin, O Mete - Advances in Anatomic Pathology, 2023 - journals.lww.com
Abstract Adrenal paraganglioma (or “pheochromocytoma”) and extra-adrenal
paraganglioma, collectively abbreviated PPGL, are rare but spectacular nonepithelial …

MicroRNAs and long non-coding RNAs in adrenocortical carcinoma

M Detomas, C Pivonello, B Pellegrini, LS Landwehr… - Cells, 2022 - mdpi.com
Non-coding RNAs (ncRNAs) are a type of genetic material that do not encode proteins but
regulate the gene expression at an epigenetic level, such as microRNAs (miRNAs) and long …

Morphological harbingers of ARMC5-pathogenic variant-related bilateral macronodular adrenocortical disease

MLA de Arruda Botelho, MY Nishi, KB Ribeiro… - Endocrine …, 2023 - Springer
Bilateral macronodular adrenocortical disease (BMAD) is a neoplastic disease associated
with a high frequency of germline disease. Armadillo repeat containing 5 (ARMC5) …