Microbiota–gut–brain axis mechanisms in the complex network of bipolar disorders: potential clinical implications and translational opportunities
MA Ortega, MA Álvarez-Mon, C García-Montero… - Molecular …, 2023 - nature.com
Bipolar disorders (BD) represent a severe leading disabling mental condition worldwide
characterized by episodic and often progressive mood fluctuations with manic and …
characterized by episodic and often progressive mood fluctuations with manic and …
[HTML][HTML] Circadian rhythms and mood disorders: Time to see the light
HK Dollish, M Tsyglakova, CA McClung - Neuron, 2024 - cell.com
The importance of time is ever prevalent in our world, and disruptions to the normal
light/dark and sleep/wake cycle have now become the norm rather than the exception for a …
light/dark and sleep/wake cycle have now become the norm rather than the exception for a …
Mapping neurotransmitter systems to the structural and functional organization of the human neocortex
Neurotransmitter receptors support the propagation of signals in the human brain. How
receptor systems are situated within macro-scale neuroanatomy and how they shape …
receptor systems are situated within macro-scale neuroanatomy and how they shape …
Neural network of bipolar disorder: Toward integration of neuroimaging and neurocircuit-based treatment strategies
B Bi, D Che, Y Bai - Translational Psychiatry, 2022 - nature.com
Bipolar disorder (BD) is a complex psychiatric disorder characterized by dysfunctions in
three domains including emotional processing, cognitive processing, and psychomotor …
three domains including emotional processing, cognitive processing, and psychomotor …
Schizophrenia, bipolar and major depressive disorders: overview of clinical features, neurotransmitter alterations, pharmacological interventions, and impact of …
PK Mandal, S Gaur, RG Roy, A Samkaria… - ACS Chemical …, 2022 - ACS Publications
Psychiatric disorders are one of the leading causes of disability worldwide and affect the
quality of life of both individuals and the society. The current understanding of these …
quality of life of both individuals and the society. The current understanding of these …
Neurobiology of bipolar disorders: a review of genetic components, signaling pathways, biochemical changes, and neuroimaging findings
Bipolar disorder (BD) is a chronic mental illness characterized by changes in mood that
alternate between mania and hypomania or between depression and mixed states, often …
alternate between mania and hypomania or between depression and mixed states, often …
Therapeutic interventions to mitigate mitochondrial dysfunction and oxidative stress–induced damage in patients with bipolar disorder
S Madireddy, S Madireddy - International Journal of Molecular Sciences, 2022 - mdpi.com
Bipolar disorder (BD) is characterized by mood changes, including recurrent manic,
hypomanic, and depressive episodes, which may involve mixed symptoms. Despite the …
hypomanic, and depressive episodes, which may involve mixed symptoms. Despite the …
Ion channels and transporters as therapeutic agents: from biomolecules to supramolecular medicinal chemistry
G Picci, S Marchesan, C Caltagirone - Biomedicines, 2022 - mdpi.com
Ion channels and transporters typically consist of biomolecules that play key roles in a large
variety of physiological and pathological processes. Traditional therapies include many ion …
variety of physiological and pathological processes. Traditional therapies include many ion …
Plasmalogen in the brain: Effects on cognitive functions and behaviors attributable to its properties
J Udagawa, K Hino - Brain research bulletin, 2022 - Elsevier
Ether phospholipid compositions are altered in the plasma or brain of patients with brain
disorders, such as Alzheimer and Parkinson's disease, including those with psychiatric …
disorders, such as Alzheimer and Parkinson's disease, including those with psychiatric …
GWAS-identified bipolar disorder risk allele in the FADS1/2 gene region links mood episodes and unsaturated fatty acid metabolism in mutant mice
H Yamamoto, HC Lee-Okada, M Ikeda… - Molecular …, 2023 - nature.com
Large-scale genome-wide association studies (GWASs) on bipolar disorder (BD) have
implicated the involvement of the fatty acid desaturase (FADS) locus. These enzymes …
implicated the involvement of the fatty acid desaturase (FADS) locus. These enzymes …