The Japanese Society of Hypertension (JSH) revised the Guidelines for the Management of
Hypertension 2014 (JSH 2014), and published the JSH 2019. In the development of the JSH …

Summary Each year, the American Heart Association (AHA), in conjunction with the Centers
for Disease Control and Prevention, the National Institutes of Health, and other government …

Aims Renin–angiotensin–aldosterone system (RAAS) inhibitors are well established for the
reduction in cardiovascular morbidity, but their impact on all-cause mortality in hypertensive …

Atrial fibrillation (AF) is the most common cardiac arrhythmia. Patients with AF have up to
seven-fold higher risk of suffering from ischemic stroke. Better understanding of etiologies of …

Atrial fibrillation (AF), the most commonly diagnosed arrhythmia, affects a notable
percentage of the population and constitutes a major risk factor for thromboembolic events …

Atrial fibrillation (AF), the most common sustained cardiac arrhythmia encountered in clinical
practice, is associated with increased morbidity and mortality. Electrophysiologically, it is …

BACKGROUND: The renin–angiotensin–aldosterone system is suggested to play a key role
in the development of atrial fibrillation through structural and electrical remodeling. This …

Obesity and diabetes can lead to heart failure with preserved ejection fraction (HFpEF),
potentially because they both cause expansion and inflammation of epicardial adipose …

The activation of transforming growth factor-β1 (TGF-β1)/Smad signaling pathway and
increased expression of connective tissue growth factor (CTGF) induced by angiotensin II …

Atrial fibrillation (AF) occurs in up to 11% of cancer patients treated with ibrutinib. The
pathophysiology of ibrutinib promoted AF is complicated, as there are multiple interactions …