Protein arginine methyltransferases (PRMTs) catalyze the methyl transfer to the arginine
residues of protein substrates and are classified into three major types based on the final …

PRMT1, the major protein arginine methyltransferase in mammals, catalyzes
monomethylation and asymmetric dimethylation of arginine side chains in proteins. Initially …

Fluoxetine has been recognized as one of the most toxic pharmaceuticals in the aquatic
environment. Since there is growing evidence that the toxic potential of fluoxetine in surface …

Protein arginine methyltransferase 1 (PRMT1) is a major type I arginine methyltransferase
that catalyzes the formation of monomethyl and asymmetric dimethylarginine in protein …

Much progress has been made toward generating analogs of early embryos, such as
gastruloids and embryoids, in vitro. However, methods for how to fully mimic the cell …

The role of epigenetics in development has garnered attention in recent years due to their
ability to modulate the embryonic developmental gene expression in response to the …

The methylation of arginine residues by protein arginine methyltransferases (PRMTs) is a
type of post-translational modification which is important for numerous cellular processes …

Protein arginine methylation is catalyzed by members of the protein arginine
methyltransferase (PRMT) family. In the present review, nine PRMTs identified in mammals …

Retinoids are morphogens and have been implicated in cell fate commitment of embryonic
stem cells (ESCs) to neurons. Their effects are mediated by RAR and RXR nuclear …

Doxorubicin (Dox) is a widely used anti-cancer drug that has a significant limitation, which is
cardiotoxicity. Its cardiotoxic side effect is dose dependent and occurs through any age. Dox …