Qualitative and quantitative testing of circulating cell free DNA (CCFDNA) can be applied for
the management of malignant and benign neoplasms. Detecting circulating DNA in cancer …

Steroid receptors in the stromal cells of endometrium and its disease counterpart tissue
endometriosis play critical physiologic roles. We found that mRNA and protein levels of …

Estrogen receptor (ER)-β is thought to exert anti-proliferative effects in the normal prostate
but supports prostate cancer (PCa) cell survival. We previously reported that the receptor's …

One plausible mechanism for the environment to alter cancer susceptibility is through DNA
methylation. Alterations in DNA methylation can lead to genomic instability and altered gene …

Background Epigenetic gene silencing is one of the major causes of carcinogenesis. Its
widespread occurrence in cancer genome could inactivate many cellular pathways …

We provide a brief overview of the structural characteristics of the main groups of conjugated
polyelectrolytes (CPEs) as well as the methods of synthesis and their behaviour in solution …

Purpose: Urokinase (uPA) is expressed in a number of highly invasive malignancies
including breast cancer. Because production of uPA is associated with breast cancer …

Objective: The human kallikrein 10 (KLK10)/normal epithelial cell-specific-1 (NES1) gene is
highly expressed in normal mammary, ovary and prostate cells, but its expression is …

Global decreases in DNA methylation, particularly in repetitive elements, have been
associated with genomic instability and human cancer. Emerging, though limited, data …

Increasing evidence demonstrated that inactivation of tumor suppressor genes (TSGs) by
aberrant promoter methylation is an early event during carcinogenesis. Aiming at …