mRNA-based cancer therapeutics

C Liu, Q Shi, X Huang, S Koo, N Kong, W Tao - Nature Reviews Cancer, 2023 - nature.com
Due to the fact that mRNA technology allows the production of diverse vaccines and
treatments in a shorter time frame and with reduced expense compared to conventional …

mRNA vaccines for infectious diseases: principles, delivery and clinical translation

N Chaudhary, D Weissman… - Nature reviews Drug …, 2021 - nature.com
Over the past several decades, messenger RNA (mRNA) vaccines have progressed from a
scepticism-inducing idea to clinical reality. In 2020, the COVID-19 pandemic catalysed the …

Organic photosensitizers for antimicrobial phototherapy

VN Nguyen, Z Zhao, BZ Tang, J Yoon - Chemical Society Reviews, 2022 - pubs.rsc.org
Microbial infectious diseases, especially those caused by new and antibiotic-resistant
pathogenic microbes, have become a significant threat to global human health. As an …

Nanotechnology-based strategies against SARS-CoV-2 variants

X Huang, E Kon, X Han, X Zhang, N Kong… - Nature …, 2022 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has already infected more
than 500 million people globally (as of May 2022), creating the coronavirus disease 2019 …

Nanotechnology as a novel approach in combating microbes providing an alternative to antibiotics

B Mubeen, AN Ansar, R Rasool, I Ullah, SS Imam… - Antibiotics, 2021 - mdpi.com
The emergence of infectious diseases promises to be one of the leading mortality factors in
the healthcare sector. Although several drugs are available on the market, newly found …

Cell membrane-coated mimics: a methodological approach for fabrication, characterization for therapeutic applications, and challenges for clinical translation

V Chugh, K Vijaya Krishna, A Pandit - ACS nano, 2021 - ACS Publications
Cell membrane-coated (CMC) mimics are micro/nanosystems that combine an isolated cell
membrane and a template of choice to mimic the functions of a cell. The design exploits its …

Bioactive synthetic polymers

K Jung, N Corrigan, EHH Wong, C Boyer - Advanced Materials, 2022 - Wiley Online Library
Synthetic polymers are omnipresent in society as textiles and packaging materials, in
construction and medicine, among many other important applications. Alternatively, natural …

Photo-sono interfacial engineering exciting the intrinsic property of herbal nanomedicine for rapid broad-spectrum bacteria killing

H Liu, J Li, X Liu, Z Li, Y Zhang, Y Liang, Y Zheng… - ACS …, 2021 - ACS Publications
Large doses and long duration are often required for herbal medicines to kill bacteria
effectively. Herein, a photoacoustic interfacial engineering strategy was utilized to endow …

Engineered spindles of little molecules around electrospun nanofibers for biphasic drug release

H He, M Wu, J Zhu, Y Yang, R Ge, DG Yu - Advanced Fiber Materials, 2021 - Springer
Biphasic drug release is a popular advanced drug controlled release profile that has been
drawing increasing attention from many fields. Electrospun nanofibers and their derivatives …

Chemical reaction-mediated covalent localization of bacteria

H Luo, Y Chen, X Kuang, X Wang, F Yang… - Nature …, 2022 - nature.com
Methods capable of manipulating bacterial colonization are of great significance for
modulating host-microbiota relationships. Here, we describe a strategy of in-situ chemical …