Recent literature shows that exercise is not simply a way to generate a calorie deficit as an
add-on to restrictive diets but exerts powerful additional biological effects via its impact on …

Background Evidence is accumulating that nutritional exposures in utero can influence
health outcomes in later life. Animal studies and human epidemiological studies have …

Background Childhood maltreatment including abuse and neglect has been associated with
adult obesity, but evidence on life-course development of obesity or BMI gain is unclear. We …

Obesity constitutes a major global health threat. Despite the success of bariatric surgery in
delivering sustainable weight loss and improvement in obesity-related morbidity, effective …

In modern societies, ageing and obesity represent medical challenges for healthcare
professionals and caregivers. Obesity and ageing share common features including the …

Background Maternal obesity prior to or during pregnancy influences fetal growth,
predisposing the offspring to increased risk for obesity across the life course. Placental …

Obesity and being overweight have become a worldwide epidemic affecting more than 1.9
billion adults and 340 million children. Efforts to curb this global health burden by …

Although recent increases in availability of energy dense, processed foods and reductions in
institutionally driven physical activity have created an environment that is permissible for …

Pediatric obesity is one of the most relevant health issues of the last century. Obesity-related
short and long-term consequences are responsible of a large amount of economic cost. In …

Results: Cross-sectional analysis identified 310 CpGs associated with BMI with P< 1.0× 10−
7, 225 of which had not been reported previously. Of these 225 novel associations, 172 …