Epigenetic mechanisms are proposed as an important way in which the genome responds
to the environment. Epigenetic marks, including DNA methylation and Histone modifications …

Skeletal muscle mass, quality and adaptability are fundamental in promoting muscle
performance, maintaining metabolic function and supporting longevity and healthspan …

Abstract Model-based analysis of ChIP-seq (MACS) is a computational algorithm that
identifies genome-wide locations of transcription/chromatin factor binding or histone …

Epilepsy is a frequent neurological disorder, although onset and progression of seizures
remain difficult to predict in affected patients, irrespective of their epileptogenic condition …

A decline in skeletal muscle mass and function with aging is well recognized, but remains
poorly characterized at the molecular level. Here, we report for the first time a genome‐wide …

Background The growing interest in the role of epigenetic modifications in human health and
disease has led to the development of next-generation sequencing methods for whole …

Abstract Background The Hemiptera (aphids, cicadas, and true bugs) are a key insect order,
with high diversity for feeding ecology and excellent experimental tractability for molecular …

Living organisms are constantly exposed to wide ranges of environmental cues. They react
to these cues by undergoing a battery of phenotypic responses, such as by altering their …

A major fraction of the transcriptome of higher organisms comprised an extensive repertoire
of long non-coding RNA (lncRNA) which express in a cell type and development stage …

Abstract Characterization of DNA methylation patterns in the Pacific oyster, Crassostrea
gigas, indicates that this epigenetic mechanism plays an important functional role in gene …