Epigenetics, plasticity, and evolution: How do we link epigenetic change to phenotype?
EJ Duncan, PD Gluckman… - Journal of Experimental …, 2014 - Wiley Online Library
Epigenetic mechanisms are proposed as an important way in which the genome responds
to the environment. Epigenetic marks, including DNA methylation and Histone modifications …
to the environment. Epigenetic marks, including DNA methylation and Histone modifications …
Does skeletal muscle have an 'epi'‐memory? The role of epigenetics in nutritional programming, metabolic disease, aging and exercise
AP Sharples, CE Stewart, RA Seaborne - Aging cell, 2016 - Wiley Online Library
Skeletal muscle mass, quality and adaptability are fundamental in promoting muscle
performance, maintaining metabolic function and supporting longevity and healthspan …
performance, maintaining metabolic function and supporting longevity and healthspan …
Identifying ChIP-seq enrichment using MACS
Abstract Model-based analysis of ChIP-seq (MACS) is a computational algorithm that
identifies genome-wide locations of transcription/chromatin factor binding or histone …
identifies genome-wide locations of transcription/chromatin factor binding or histone …
[HTML][HTML] Deep sequencing reveals increased DNA methylation in chronic rat epilepsy
Epilepsy is a frequent neurological disorder, although onset and progression of seizures
remain difficult to predict in affected patients, irrespective of their epileptogenic condition …
remain difficult to predict in affected patients, irrespective of their epileptogenic condition …
Genome‐wide DNA methylation changes with age in disease‐free human skeletal muscle
A Zykovich, A Hubbard, JM Flynn, M Tarnopolsky… - Aging cell, 2014 - Wiley Online Library
A decline in skeletal muscle mass and function with aging is well recognized, but remains
poorly characterized at the molecular level. Here, we report for the first time a genome‐wide …
poorly characterized at the molecular level. Here, we report for the first time a genome‐wide …
[HTML][HTML] Molecular evolutionary trends and feeding ecology diversification in the Hemiptera, anchored by the milkweed bug genome
KA Panfilio, IM Vargas Jentzsch, JB Benoit… - Genome biology, 2019 - Springer
Abstract Background The Hemiptera (aphids, cicadas, and true bugs) are a key insect order,
with high diversity for feeding ecology and excellent experimental tractability for molecular …
with high diversity for feeding ecology and excellent experimental tractability for molecular …
[HTML][HTML] Focused, high accuracy 5-methylcytosine quantitation with base resolution by benchtop next-generation sequencing
Background The growing interest in the role of epigenetic modifications in human health and
disease has led to the development of next-generation sequencing methods for whole …
disease has led to the development of next-generation sequencing methods for whole …
Can epigenetics translate environmental cues into phenotypes?
P Norouzitallab, K Baruah, D Vanrompay… - Science of the Total …, 2019 - Elsevier
Living organisms are constantly exposed to wide ranges of environmental cues. They react
to these cues by undergoing a battery of phenotypic responses, such as by altering their …
to these cues by undergoing a battery of phenotypic responses, such as by altering their …
[HTML][HTML] Predominant intragenic methylation is associated with gene expression characteristics in a bivalve mollusc
MR Gavery, SB Roberts - PeerJ, 2013 - peerj.com
Abstract Characterization of DNA methylation patterns in the Pacific oyster, Crassostrea
gigas, indicates that this epigenetic mechanism plays an important functional role in gene …
gigas, indicates that this epigenetic mechanism plays an important functional role in gene …
Genome-wide analysis reveals distinct patterns of epigenetic features in long non-coding RNA loci
A major fraction of the transcriptome of higher organisms comprised an extensive repertoire
of long non-coding RNA (lncRNA) which express in a cell type and development stage …
of long non-coding RNA (lncRNA) which express in a cell type and development stage …