Interdisciplinary fetal-neonatal neurology training applies neural exposome perspectives to neurology principles and practice

MS Scher - Frontiers in neurology, 2024 - frontiersin.org
An interdisciplinary fetal-neonatal neurology (FNN) program over the first 1,000 days
teaches perspectives of the neural exposome that are applicable across the life span. This …

A bio-social model during the first 1000 days optimizes healthcare for children with developmental disabilities

MS Scher - Biomedicines, 2022 - mdpi.com
Most children with developmental disabilities (DD) live in resource-limited countries (LMIC)
or high-income country medical deserts (HICMD). A social contract between healthcare …

The association of placental pathology and neurodevelopmental outcomes in patients with neonatal encephalopathy

AC Stone, KC Strickland, DT Tanaka, JB Gilner… - Pediatric …, 2023 - nature.com
Background Studies conflict on how acute versus chronic placental pathology impacts
outcomes after neonatal encephalopathy from presumed hypoxic-ischemic encephalopathy …

Prematurity and low birth weight and their impact on childhood growth patterns and the risk of long-term cardiovascular sequelae

I Jańczewska, J Wierzba, A Jańczewska… - Children, 2023 - mdpi.com
Preterm birth (before 37 completed weeks of gestation) is a global health problem,
remaining the main reason for neonatal mortality and morbidity. Improvements in perinatal …

Viral infections in pregnancy and impact on offspring neurodevelopment: mechanisms and lessons learned

EF Yates, SB Mulkey - Pediatric research, 2024 - nature.com
Pregnant individuals with viral illness may experience significant morbidity and have higher
rates of pregnancy and neonatal complications. With the growing number of viral infections …

The science of uncertainty guides fetal-neonatal neurology principles and practice: diagnostic-prognostic opportunities and challenges

MS Scher - Frontiers in Neurology, 2024 - frontiersin.org
Fetal-neonatal neurologists (FNNs) consider diagnostic, therapeutic, and prognostic
decisions strengthened by interdisciplinary collaborations. Bio-social perspectives of the …

The neural exposome influences the preterm fetal-to-neonatal connectome

MS Scher - Pediatric Research, 2024 - nature.com
Plomgaard et al. present preliminary results using “a priori defined analysis” suggesting an
association between an automated computational measure of electroencephalogram …

Gene-environment interactions during the first thousand days influence childhood neurological diagnosis

MS Scher - Seminars in Pediatric Neurology, 2022 - Elsevier
Gene-environment (G x E) interactions significantly influence neurologic outcomes. The
maternal-placental-fetal (MPF) triad, neonate, or child less than 2 years may first exhibit …

Prenatal neurological diagnosis: challenges in neuroimaging, prognostic counseling, and prediction of neurodevelopmental outcomes

S Agarwal, T Tarui, V Patel, A Turner, U Nagaraj… - Pediatric Neurology, 2023 - Elsevier
Prenatal diagnosis of fetal brain abnormalities is rapidly evolving with the advancement of
neuroimaging techniques, thus adding value to prognostic counseling and perinatal …

Molecular indicators of blood-brain barrier breakdown and neuronal injury in pregnancy complicated by fetal growth restriction

N Misan, S Michalak, P Rzymski… - International journal of …, 2022 - mdpi.com
This study evaluated the damage to the endothelial tight junctions (TJs) in pregnancies
complicated by fetal growth restriction (FGR) and investigated whether FGR is related to …