For pediatric kidney transplant physicians, two aspects of Alport syndrome set the disease
apart from other causes of terminal renal failure. First, an understanding of the genetics of …

Screening healthy children for abnormalities in the urine has shown that microhematuria is
common and often transient [1, 2]. Evaluation of pediatric patients with persistent, isolated …

Familial glomerular hematuria (s) comprise a genetically heterogeneous group of conditions
which include Alport Syndrome (AS) and thin basement membrane nephropathy (TBMN) …

Familial microscopic hematuria (FMH) is associated with a genetically heterogeneous group
of conditions including the collagen‐IV nephropathies, the heritable C3/CFHR5 nephropathy …

Both thin basement membrane nephropathy (TBMN) and autosomal recessive Alport
syndrome result from mutations in the COL4A3 and COL4A4 genes, and this study …

Renal biopsy was introduced in the 1950s. By 1980 the pathologic diagnostic criteria for the
majority of medical kidney diseases known today, including pediatric diseases, were …

Aim Although asymptomatic gross haematuria (GHU) is relatively common in children, its
causes and clinical outcomes are not clearly defined. Methods Children with asymptomatic …

The Col4A3, Col4A4 and Col4A5 collagen type IV genes are found to be mutated in Col IV
nephropathy. In males with a mutation in the Col4A5 gene (X-linked Alport syndrome: XL …

Slajpah et al.[1] entitled The importance of non-invasive genetic analysis in the initial
diagnosis of Alport syndrome in young patients. Genetic technology now provides us with …

We examined a group of 83 patients (57 children and 26 adults) with thin basement
membrane disease and 17 patients with Alport syndrome. We compared the clinical data …