Aortic aneurysm, including thoracic aortic aneurysm and abdominal aortic aneurysm, is the
second most prevalent aortic disease following atherosclerosis, representing the ninth …

Aortic aneurysm is a chronic aortic disease affected by many factors. Although it is generally
asymptomatic, it poses a significant threat to human life due to a high risk of rupture …

Abdominal aortic aneurysm (AAA) is a lethal degenerative vascular disease that affects,
mostly, the elder population, with a high mortality rate (> 80%) upon rupture. It features a …

Oxidative stress (OS) refers to the enhancement of oxidation and the decreased of related
antioxidant enzymes activity under pathological conditions, resulting in relatively excess …

BACKGROUND: Smooth muscle cell (SMC) phenotypic switching has been increasingly
detected in aortic aneurysm and dissection (AAD) tissues. However, the diverse SMC …

Inadequate adaption to mechanical forces, including blood pressure, contributes to
development of arterial aneurysms. Recent studies have pointed to a mechanoprotective …

Abdominal aortic aneurysm (AAA) is a common vascular disease associated with significant
phenotypic alterations in vascular smooth muscle cells (VSMCs). Gasdermin D (GSDMD) is …

Abdominal aortic aneurysm (AAA) is a chronic vascular disease caused by localized
weakening and broadening of the abdominal aorta. AAA is a clearly underdiagnosed …

Objectives: This study aimed to identify key AAA-related m1A RNA methylation regulators
and their association with immune infiltration in AAA. Furthermore, we aimed to explore the …

The neutrophil plays an important role during abdominal aortic aneurysm (AAA) formation by
undergoing histone citrullination with peptidyl arginine deiminase 4 (encoded by Padi4) and …