Any alteration at the genetic or epigenetic level, may result in multiplex of diseases including
tumorigenesis which ultimately results in the cancer development. Restoration of the normal …

Ferroptosis is a newly recognized form of oxidative-regulated cell death resulting from iron-
mediated lipid peroxidation accumulation. Radical-trapping antioxidant systems can …

Among all cancers, colorectal cancer (CRC) is the 3rd most common and the 2nd leading
cause of death worldwide. New therapeutic strategies are required to target cancer stem …

Oncogenic driver mutations have implications that extend beyond cancer cells themselves.
Aberrant tumour cell signalling has various effects on the tumour microenvironment and anti …

Histone modifications are key factors in chromatin packaging, and are responsible for gene
regulation during cell fate determination and development. Abnormal alterations in histone …

Adenoid cystic carcinoma (ACC) has a worldwide incidence of three to four cases per million
population. Although more cases occur in the minor and major salivary glands, it is the most …

Simple Summary Epigenetics encompasses all the modifications that occur within cells that
are independent of gene mutations. The environment is the main influencer of these …

Epigenetic regulation and Focal adhesion kinase (FAK) are considered to be two important
targets for the development of antitumor drugs. Studies have shown that the combination of …

Aims Therapeutic outcome of sorafenib in hepatocellular carcinoma (HCC) is undermined
by the development of drug resistance. This study aimed to identify the critical microRNA …

Many natural products can exert anticancer or chemopreventive activity by interfering with
the cellular epigenetic machinery. Many studies indicate the relevance of affecting DNA …