Background Epigenetic silencing of tumor suppressor genes (TSGs) is a key feature of
oncogenesis in hepatocellular carcinoma (HCC). Liver-targeted delivery of CRISPR …

Medullary thyroid carcinoma (MTC) is a C-cell-derived epithelial neuroendocrine neoplasm.
With the exception of rare examples, most are well-differentiated epithelial neuroendocrine …

Abstract N-acetyltransferase 10 (NAT10), a versatile enzyme, has gained considerable
attention as a significant player in the complex realm of cancer biology. Its enigmatic role in …

TNFα and IFN-γ secreted by CD4+ T-Helper (TH) cells have antitumor activity followed by
polarisation of TH 1 phenotype in response to IL-12 secreted by dendritic cells, inducing …

Human papillomavirus (HPV) infection is the leading cause of cervical cancer. The
Papanicolaou cytology test is the usually employed type of screening for this infection; …

Triple-negative breast cancer (TNBC) is the most malignant subtype of breast cancer. In the
absence of effective molecular markers for TNBC, there is an urgent clinical need for …

Dysregulation of epigenetic mechanisms has been recognized to play a crucial role in
cancer development, but these mechanisms vary between sexes. Therefore, we focused on …

Breast cancer remains a major global health challenge. Its rising incidence is attributed to
factors such as delayed diagnosis, the complexity of its subtypes, and increasing drug …

Serum and glucocorticoid-regulated kinase 1 (SGK1) is a Ser/Thr protein kinase involved in
regulating cell survival, growth, proliferation, and migration. Its elevated expression and …

After fertilization, sperm and oocyte fused and gave rise to a zygote which is the beginning of
a new life. Then the embryonic development is monitored and regulated precisely from the …