The functionality of sense–antisense transcripts (SATs), although widespread throughout the
mammalian genome, is largely unknown. Here, we analyzed the SATs expression and its …

The fibrinogen genes FGA, FGB and FGG show coordinated expression in hepatocytes.
Understanding the underlying transcriptional regulation may elucidate how their tissue …

CpG 岛甲基化在细胞的各种生物过程中扮演着重要角色. 开发了预测人类基因组CpG
岛甲基化状态的计算模型, 获得了目前最好的预测性能, 并用此模型对人类全基因组的CpG …

Nodal signaling plays critical roles during embryonic development. The Nodal gene is not
expressed in adult tissues but is frequently activated in cancer cells, contributing to …

Cell differentiation involves widespread epigenetic reprogramming, including modulation of
DNA methylation patterns. The differentiation potential differences in DNA methylation …

DNA methylation in transcriptional regulatory regions is crucial for gene expression. The
DNA methylation status of the edges of CpG islands, called CpG island shore, is involved in …

The aim of this study was to investigate the association and expression of HNF1A gene as a
candidate gene for meat and carcass quality traits in pigs. Statistical analysis revealed that …

DNA methylation is a well-characterized epigenetic landmark involved in transcriptional
regulation; however, mechanisms underlying its regulation remain poorly characterized …

Measurement of carcinogen DNA adducts in blood has been used as a surrogate for the
target lung tissue. We aimed to examine whether genetic polymorphisms in several …

Normal thyroid tissue displays a prevalent expression of ERβ than ERα, which drastically
turns upside down in the initiation and progression of papillary thyroid cancer (PTC). The …