Drug processing genes (DPGs), namely uptake transporters, phase-I and phase-II enzymes,
as well as efflux transporters are responsible for the absorption, distribution, metabolism …

Recurrent miscarriage (RM) is a complex clinical problem. However, specific diagnostic
biomarkers and candidate regulatory targets have not yet been identified. To explore RM …

Organic anion transporting polypeptides (rodents, Oatps; human, OATPs) are primarily
involved in the transmembrane transportation of a wide range of endogenous and …

Differential methylation of imprinting control regions in mammals is essential for
distinguishing the parental alleles from each other and regulating their expression …

In mammalian livers, sexual dimorphisms are observed in tissue-specific functions and
diseases such as hepatocellular carcinoma. We identified sex-dependent differentially …

The genome-wide variation of multiple epigenetic modifications in CpG islands (CGIs) and
the interactions between them are of great interest. Here, we optimized an entropy-based …

The α7 nicotinic acetylcholine receptor is known to regulate a wide variety of developmental
and secretory functions in neural and non-neural tissues. The mechanisms that regulate its …

Investigating differentially methylated regions (DMRs) presented in different tissues or cell
types can help to reveal the mechanisms behind the tissue-specific gene expression. The …

Six1, an evolutionary conserved transcription factor, has been shown to play an important
role in organogenesis and diseases. However, no reports were shown to investigate its …

DNA methylation-dependent gene silencing is one of the most characterized mechanisms in
epigenetic regulation of gene expression. This process is thought to influence the ability of …