The human brain in a high altitude natural environment: A review

X Zhang, J Zhang - Frontiers in Human Neuroscience, 2022 - frontiersin.org
With the advancement of in vivo magnetic resonance imaging (MRI) technique, more
detailed information about the human brain at high altitude (HA) has been revealed. The …

Resting-state neuronal activity and functional connectivity changes in the visual cortex after high altitude exposure: a longitudinal study

X Zhang, T Kang, Y Liu, F Yuan, M Li, J Lin, J Zhang - Brain Sciences, 2022 - mdpi.com
Damage to the visual cortex structures after high altitude exposure has been well clarified.
However, changes in the neuronal activity and functional connectivity (FC) of the visual …

Brain structure and neurocognitive function in two professional mountaineers during 35 days of severe normobaric hypoxia

SE Sönksen, S Kühn, M Basner… - European journal of …, 2022 - Wiley Online Library
Background and purpose Animal studies suggest that exposure to severe ambient hypoxia
for several days may have beneficial long‐term effects on neurodegenerative diseases …

Beet on Alps: Time-course changes of plasma nitrate and nitrite concentrations during acclimatization to high-altitude

L Rasica, S Porcelli, U Limper, S Mrakic-Sposta… - Nitric Oxide, 2021 - Elsevier
Nitric oxide seems to be involved in the altitude acclimatization process due to its ability to
regulate pulmonary, cardiovascular and muscular responses to hypoxia. In this study, we …

Altitude-related features and prognosis in patients with reversible splenial lesion syndrome

HX Wang, YD Li, J Liang, YZ Xue, L Zhu… - Annals of …, 2024 - Taylor & Francis
Introduction RESLES (Reversible splenial lesion syndrome) can be observed secondary to
various diseases, and intramyelinic edema may play a crucial role in the pathogenesis of …

High-altitude exposure duration dependent global and regional gray matter volume decrease in healthy immigrants: a cross-sectional study

J Feng, W Men, X Yu, W Liu, S Zhang, J Liu… - Acta …, 2023 - journals.sagepub.com
Background The correlation between brain injury and high-altitude (HA) exposure duration
(Dur_HA) as well as peripheral oxygen saturation (SpO2) remains unclear. Purpose To …

High altitude is associated with pTau deposition, neuroinflammation, and myelin loss

D Iacono, EK Murphy, PM Sherman, H Chapapas… - Scientific reports, 2022 - nature.com
Mammals are able to adapt to high altitude (HA) if appropriate acclimation occurs. However,
specific occupations (professional climbers, pilots, astronauts and other) can be exposed to …

Magnetic resonance imaging evaluation of suspected high-altitude cerebral edema in patients from high altitude

DB Karki, G Gurung, RK Ghimire - 2022 - elibrary.nhrc.gov.np
Background: Trekkers in high altitude of Himalayas could lead to Acute Mountain Sickness
and High Altitude Cerebral Edema. This study was conducted to evaluate magnetic …

Human Hypoxia Models: From Space Medicine to Human Pharmacological Studies

T Post, C Denney, A Cohen, J Jordan, U Limper - Authorea Preprints, 2023 - techrxiv.org
Space medicine has developed controlled terrestrial models to investigate the impacts on
human health and performance, and their application should be expanded to encompass …

Examination of novel diagnostic approaches and contemporary strategies for preventing acute mountain sickness

Z Olejarz, K Nowak, Z Drygała, J Wyrwał… - Journal of Education …, 2024 - apcz.umk.pl
Introduction and purpose: Acute mountain sickness is caused by hypoxia, of which the brain
is the most sensitive. The frequency of occurrence at altitudes above 2500 m above sea …