[HTML][HTML] A review of colorectal cancer in terms of epidemiology, risk factors, development, symptoms and diagnosis
T Sawicki, M Ruszkowska, A Danielewicz… - Cancers, 2021 - mdpi.com
Simple Summary According to the available data, colorectal cancer (CRC) is one of the most
common malignant neoplasms. Depending on the location, type of cancer or gender, it is …
common malignant neoplasms. Depending on the location, type of cancer or gender, it is …
Epigenetics of colorectal cancer: biomarker and therapeutic potential
G Jung, E Hernández-Illán, L Moreira… - Nature reviews …, 2020 - nature.com
Colorectal cancer (CRC), a leading cause of cancer-related death worldwide, evolves as a
result of the stepwise accumulation of a series of genetic and epigenetic alterations in the …
result of the stepwise accumulation of a series of genetic and epigenetic alterations in the …
[HTML][HTML] Circulating cell-free DNA for cancer early detection
Q Gao, Q Zeng, Z Wang, C Li, Y Xu, P Cui, X Zhu, H Lu… - The Innovation, 2022 - cell.com
Effective screening modalities are currently available for only a small subset of cancers, and
they generally have suboptimal performance with complicated procedures. Therefore, there …
they generally have suboptimal performance with complicated procedures. Therefore, there …
[HTML][HTML] DNA methylation-based diagnostic, prognostic, and predictive biomarkers in colorectal cancer
DNA methylation is an epigenetic mechanism regulating gene expression. Changes in DNA
methylation were suggested to be useful biomarkers for diagnosis, and for the determination …
methylation were suggested to be useful biomarkers for diagnosis, and for the determination …
Epigenetic alterations in the gastrointestinal tract: current and emerging use for biomarkers of cancer
WM Grady - Advances in cancer research, 2021 - Elsevier
Colorectal cancer is a leading cause of cancer related deaths worldwide. One of the
hallmarks of cancer and a fundamental trait of virtually all gastrointestinal cancers is …
hallmarks of cancer and a fundamental trait of virtually all gastrointestinal cancers is …
[HTML][HTML] DNA methylation-based testing in liquid biopsies as detection and prognostic biomarkers for the four major cancer types
Lung, breast, colorectal, and prostate cancers are the most incident worldwide. Optimal
population-based cancer screening methods remain an unmet need, since cancer detection …
population-based cancer screening methods remain an unmet need, since cancer detection …
Advances in tests for colorectal cancer screening and diagnosis
SCH Chan, JQ Liang - Expert review of molecular diagnostics, 2022 - Taylor & Francis
Introduction Colorectal cancer (CRC) is the second leading cause of cancer-related deaths
globally. Nonetheless, with early detection of CRC or its precancerous lesions, mortality, and …
globally. Nonetheless, with early detection of CRC or its precancerous lesions, mortality, and …
[HTML][HTML] Colorectal cancer detected by liquid biopsy 2 years prior to clinical diagnosis in the HUNT study
SS Brenne, PH Madsen, IS Pedersen, K Hveem… - British Journal of …, 2023 - nature.com
Background Colorectal cancer (CRC) is often diagnosed in advanced stages. Circulating
tumour DNA (ctDNA) has been proposed as an early diagnostic biomarker. However, as a …
tumour DNA (ctDNA) has been proposed as an early diagnostic biomarker. However, as a …
DNA methylation biomarkers in colorectal cancer: Clinical applications for precision medicine
N Fatemi, S Tierling, HA Es, M Varkiani… - … journal of cancer, 2022 - Wiley Online Library
Colorectal cancer (CRC) is the second leading cause of cancer death worldwide that is
attributed to gradual long‐term accumulation of both genetic and epigenetic changes. To …
attributed to gradual long‐term accumulation of both genetic and epigenetic changes. To …
[HTML][HTML] Early detection of colorectal cancer based on presence of methylated syndecan-2 (SDC2) in stool DNA
YD Han, TJ Oh, TH Chung, HW Jang, YN Kim, S An… - Clinical …, 2019 - Springer
Background Colorectal cancer (CRC) screening can effectively reduce disease-related
mortality by detecting CRC at earlier stages. We have previously demonstrated that the …
mortality by detecting CRC at earlier stages. We have previously demonstrated that the …