[HTML][HTML] Profiling genome-wide DNA methylation

WS Yong, FM Hsu, PY Chen - Epigenetics & chromatin, 2016 - Springer
DNA methylation is an epigenetic modification that plays an important role in regulating
gene expression and therefore a broad range of biological processes and diseases. DNA …

Green tea (Camellia sinensis) and l-theanine: Medicinal values and beneficial applications in humans—A comprehensive review

M Saeed, M Naveed, M Arif, MU Kakar… - Biomedicine & …, 2017 - Elsevier
Green tea (Camellia sinensis) is a famous herb, and its extract has been extensively used in
traditional Chinese medicinal system. In this context, several studies have revealed its …

Leptin resistance in obesity: an epigenetic landscape

AB Crujeiras, MC Carreira, B Cabia, S Andrade, M Amil… - Life sciences, 2015 - Elsevier
Leptin is an adipocyte-secreted hormone that inhibits food intake and stimulates energy
expenditure through interactions with neuronal pathways in the brain, particularly pathways …

[HTML][HTML] A novel blood-based panel of methylated DNA and protein markers for detection of early-stage hepatocellular carcinoma

NP Chalasani, TS Ramasubramanian… - Clinical …, 2021 - Elsevier
Background & Aims Hepatocellular carcinoma (HCC) can be treated effectively if detected at
an early stage. Recommended surveillance strategies for at-risk patients include ultrasound …

[HTML][HTML] The role of epigenetic change in autism spectrum disorders

YJ Loke, AJ Hannan, JM Craig - Frontiers in neurology, 2015 - frontiersin.org
Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental
disorders characterized by problems with social communication, social interaction, and …

[HTML][HTML] DNA methylation: conducting the orchestra from exposure to phenotype?

FAD Leenen, CP Muller, JD Turner - Clinical epigenetics, 2016 - Springer
Abstract DNA methylation, through 5-methyl-and 5-hydroxymethylcytosine (5mC and 5hmC),
is considered to be one of the principal interfaces between the genome and our …

[HTML][HTML] Application of artificial intelligence in diagnosis and treatment of colorectal cancer: A novel Prospect

Z Yin, C Yao, L Zhang, S Qi - Frontiers in Medicine, 2023 - frontiersin.org
In the past few decades, according to the rapid development of information technology,
artificial intelligence (AI) has also made significant progress in the medical field. Colorectal …

[HTML][HTML] Methylation biomarkers for early cancer detection and diagnosis: Current and future perspectives

J Ibrahim, M Peeters, G Van Camp… - European Journal of …, 2023 - Elsevier
The increase in recent scientific studies on cancer biomarkers has brought great new
insights into the field. Moreover, novel technological breakthroughs such as long read …

[HTML][HTML] Aberrant DNA methylation in melanoma: biomarker and therapeutic opportunities

G Micevic, N Theodosakis, M Bosenberg - Clinical epigenetics, 2017 - Springer
Aberrant DNA methylation is an epigenetic hallmark of melanoma, known to play important
roles in melanoma formation and progression. Recent advances in genome-wide …

[HTML][HTML] Molecular biomarkers for gestational diabetes mellitus

S Dias, C Pheiffer, Y Abrahams, P Rheeder… - International journal of …, 2018 - mdpi.com
Gestational diabetes mellitus (GDM) is a growing public health problem worldwide. The
condition is associated with perinatal complications and an increased risk for future …