Behavioural traits in mammals are influenced by environmental factors, which can interact
with the genome and modulate its activity by complex molecular interplay. Environmental …

Literature on maternal exposures and the risk of epigenetic changes or diseases in the
offspring is growing. Paternal contributions are often not considered. However, some animal …

Background Epigenetic reprogramming in mammalian gametes resets methylation marks
that regulate monoallelic expression of imprinted genes. In males, this involves erasure of …

Background Data from epidemiological and animal model studies suggest that nutrition
during pregnancy may affect the health status of subsequent generations. These …

Bisphenol A (BPA) is a man-made compound used to make polycarbonate plastics and
epoxy resins; public health concerns have been fueled by findings that BPA exposure can …

Accumulating evidence suggests that long non-coding RNA H19 correlates with several
aging processes. However, the role of H19 in aging remains unclear. Many studies have …

Diethylhexyl phthalate (DEHP) is an estrogen-like compound widely used as a plasticizer in
commercial products and is present in medical devices, and common household items. It is …

Sexual differentiation of the brain takes place during a perinatal-sensitive time window as a
result of gonadal hormone-induced activational and organizational effects on neuronal …

Background Obesity is a worldwide problem affecting the health of millions of people
throughout the life course. Studies reveal that obesity impairs sperm parameters and …

Preterm birth (PTB), parturition prior to 37 weeks' gestation, is the leading cause of neonatal
mortality. The causes of spontaneous PTB are poorly understood; however, recent studies …