Enhancing global access to cancer medicines

J Cortes, JM Perez‐García… - CA: a cancer journal …, 2020 - Wiley Online Library
Globally, cancer is the second leading cause of death, with numbers greatly exceeding
those for human immunodeficiency virus/acquired immunodeficiency syndrome …

Substance, use in relation to COVID-19: a scoping review

N Kumar, K Janmohamed, K Nyhan, SS Martins… - Addictive …, 2022 - Elsevier
Background We conducted a scoping review focused on various forms of substance use
amid the pandemic, looking at both the impact of substance use on COVID-19 infection …

Avoidable flaws in observational analyses: an application to statins and cancer

BA Dickerman, X García-Albéniz, RW Logan… - Nature medicine, 2019 - nature.com
The increasing availability of large healthcare databases is fueling an intense debate on
whether real-world data should play a role in the assessment of the benefit–risk of medical …

[HTML][HTML] Defining the role of real-world data in cancer clinical research: The position of the European Organisation for Research and Treatment of Cancer

R Saesen, M Van Hemelrijck, J Bogaerts… - European Journal of …, 2023 - Elsevier
The emergence of the precision medicine paradigm in oncology has led to increasing
interest in the integration of real-world data (RWD) into cancer clinical research. As sources …

Should dietary guidelines recommend low red meat intake?

F Leroy, N Cofnas - Critical Reviews in Food Science and Nutrition, 2020 - Taylor & Francis
Mainstream dietary recommendations now commonly advise people to minimize the intake
of red meat for health and environmental reasons. Most recently, a major report issued by …

Impact of regulatory guidance on evaluating cardiovascular risk of new glucose-lowering therapies to treat type 2 diabetes mellitus: lessons learned and future …

A Sharma, NJ Pagidipati, RM Califf, DK McGuire… - Circulation, 2020 - Am Heart Assoc
Responding to concerns about the potential for increased risk of adverse cardiovascular
outcomes, specifically myocardial infarction, associated with certain glucose-lowering …

Randomized Trials Versus Common Sense and Clinical Observation: JACC Review Topic of the Week

AC Fanaroff, RM Califf, RA Harrington… - Journal of the American …, 2020 - jacc.org
Concerns about the external validity of traditional randomized clinical trials (RCTs), together
with the widespread availability of real-world data and advanced data analytic tools, have …

Allergen immunotherapy: the growing role of observational and randomized trial “Real‐World Evidence”

G Paoletti, D Di Bona, DK Chu, D Firinu, E Heffler… - Allergy, 2021 - Wiley Online Library
Background Although there is a considerable body of knowledge about allergen
immunotherapy (AIT), there is a lack of data on the reliability of real‐world evidence (RWE) …

Cardiovascular outcomes of type 2 diabetic patients treated with SGLT-2 inhibitors versus GLP-1 receptor agonists in real-life

E Longato, B Di Camillo, G Sparacino… - BMJ Open Diabetes …, 2020 - drc.bmj.com
Introduction Sodium glucose cotransporter-2 inhibitors (SGLT2i) and glucagon-like peptide-
1 receptor agonists (GLP-1RA) protect type 2 diabetic (T2D) patients from cardiovascular …

Designing and undertaking randomised implementation trials: guide for researchers

L Wolfenden, R Foy, J Presseau, JM Grimshaw… - bmj, 2021 - bmj.com
Implementation science is the study of methods to promote the systematic uptake of
evidence based interventions into practice and policy to improve health. Despite the need …