C3 glomerulopathy (C3G) defines a group of very rare renal diseases in which dysregulation
of the alternative and terminal complement pathways plays a pivotal pathogenic role …

C3 glomerulopathy (C3G) is a rare set of kidney diseases with 2 patterns: C3
glomerulonephritis (C3GN) and dense deposit disease. Pathogenesis of both diseases is …

The complement system represents a major component of our innate immune defense.
Although the physiological contribution of the complement system is beneficial, it can cause …

Abstract Background: C3 glomerulopathy (C3GP) is a recently identified and described
disease that has a high risk of progressing into end-stage renal disease. We aimed to …

C3 glomerulopathy (C3G) is a newly defined clinical entity comprising glomerular lesions
with predominant C3 staining. Under this definition are now included membranoproliferative …

Annexin A2 is a Ca2+-and phospholipid-binding protein which is widely expressed in
various types of cells and tissues. As a multifunctional molecule, annexin A2 is found to be …

Abstract C3 glomerulopathy (C3G) is an ultra-rare complement-mediated renal disease
characterized histologically by the predominance of C3 deposition within in the glomerulus …

C3 glomerulopathy is a recently described form of CKD. C3GN is a subtype of C3
glomerulopathy characterized by predominant C3 deposits in the glomeruli and is commonly …

Recent advances in glomerular biology have expanded our understanding of glomerular
diseases, leading to more precise therapeutic options. Since the discovery of the …

Abstract C3 glomerulopathy (C3G) is a rare and complex kidney disease that primarily
affects young adults. Renal outcomes remain poor in the absence of specific treatment. C3G …