Secondary focal and segmental glomerulosclerosis associated with single-nucleotide polymorphisms in the genes encoding complement factor H and C3
Genetic causes of focal and segmental glomerulosclerosis (FSGS) typically involve
mutations and allele variants of genes expressed in podocytes or, more rarely, glomerular …
mutations and allele variants of genes expressed in podocytes or, more rarely, glomerular …
Shedding light on fundus drusen associated with membranoproliferative glomerulonephritis: breaking stereotypes of types I, II, and III
Purpose: Membranoproliferative glomerulonephritis (MPGN) classification has been
changed from purely anatomic to molecular. This report describes two cases of MPGN with …
changed from purely anatomic to molecular. This report describes two cases of MPGN with …
[HTML][HTML] Reclassification of membranoproliferative glomerulonephritis: Identification of a new GN: C3GN
M Salvadori, G Rosso - World Journal of Nephrology, 2016 - ncbi.nlm.nih.gov
This review revises the reclassification of the membranoproliferative glomerulonephritis
(MPGN) after the consensus conference that by 2015 reclassified all the glomerulonephritis …
(MPGN) after the consensus conference that by 2015 reclassified all the glomerulonephritis …
[HTML][HTML] C5 inhibition prevents renal failure in a mouse model of lethal C3 glomerulopathy
AL Williams, D Gullipalli, Y Ueda, S Sato, L Zhou… - Kidney international, 2017 - Elsevier
C3 glomerulopathy is a potentially life-threatening disease of the kidney caused by
dysregulated alternative pathway complement activation. The specific complement mediator …
dysregulated alternative pathway complement activation. The specific complement mediator …
C4 glomerulopathy: a disease entity associated with C4d deposition
S Sethi, PS Quint, CM O'Seaghdha… - American journal of …, 2016 - Elsevier
Complement-mediated glomerulonephritis, which includes C3 glomerulopathy, is
characterized by dominant staining of C3 with minimal or no immunoglobulin deposits on …
characterized by dominant staining of C3 with minimal or no immunoglobulin deposits on …
C3 glomerulonephritis and CFHR5 nephropathy
DP Gale, PH Maxwell - Nephrology Dialysis Transplantation, 2013 - academic.oup.com
Complement is an important aspect of defence against infection and its activation and
regulation are finely balanced. Disordered complement regulation can lead to C3 …
regulation are finely balanced. Disordered complement regulation can lead to C3 …
[HTML][HTML] De novo glomerular diseases after renal transplantation: How is it different from recurrent glomerular diseases?
F Abbas, M El Kossi, JK Jin, A Sharma… - World Journal of …, 2017 - ncbi.nlm.nih.gov
The glomerular diseases after renal transplantation can occur de novo, ie., with no relation
to the native kidney disease, or more frequently occur as a recurrence of the original disease …
to the native kidney disease, or more frequently occur as a recurrence of the original disease …
C3 nephritic factor associated with C3 glomerulopathy in children
C Nicolas, V Vuiblet, V Baudouin, MA Macher… - Pediatric …, 2014 - Springer
Abstract Background C3 glomerulopathy (C3G) is characterized by predominant C3
deposits in glomeruli and dysregulation of the alternative pathway of complement. Half of …
deposits in glomeruli and dysregulation of the alternative pathway of complement. Half of …
Optimal conditions and the advantages of using laser microdissection and liquid chromatography tandem mass spectrometry for diagnosing renal amyloidosis
M Aoki, D Kang, A Katayama, N Kuwahara… - Clinical and …, 2018 - Springer
Background Liquid chromatography-tandem mass spectrometry (LC-MS/MS) has recently
been utilized to accurately detect the amyloid proteins of renal amyloidosis. The present …
been utilized to accurately detect the amyloid proteins of renal amyloidosis. The present …
[HTML][HTML] Novel assays to distinguish between properdin-dependent and properdin-independent C3 nephritic factors provide insight into properdin-inhibiting therapy
MAHM Michels, NCAJ Van de Kar… - Frontiers in …, 2019 - frontiersin.org
C3 glomerulopathy (C3G) is an umbrella classification for severe renal diseases
characterized by predominant staining for complement component C3 in the glomeruli. The …
characterized by predominant staining for complement component C3 in the glomeruli. The …