Regulatory mechanisms of epigenetic miRNA relationships in human cancer and potential as therapeutic targets

KMT Arif, EK Elliott, LM Haupt, LR Griffiths - Cancers, 2020 - mdpi.com
Simple Summary By the virtue of targeting multiple genes, a microRNA (miRNA) can infer
variable consequences on tumorigenesis by appearing as both a tumour suppressor and …

Histone modifications and non-coding RNAs: mutual epigenetic regulation and role in pathogenesis

IV Bure, MV Nemtsova, EB Kuznetsova - International Journal of …, 2022 - mdpi.com
In the last few years, more and more scientists have suggested and confirmed that
epigenetic regulators are tightly connected and form a comprehensive network of regulatory …

Physical activity and DNA methylation in humans

WJ Światowy, H Drzewiecka, M Kliber… - International journal of …, 2021 - mdpi.com
Physical activity is a strong stimulus influencing the overall physiology of the human body.
Exercises lead to biochemical changes in various tissues and exert an impact on gene …

Developing a cancer digital twin: supervised metastases detection from consecutive structured radiology reports

KE Batch, J Yue, A Darcovich, K Lupton… - Frontiers in artificial …, 2022 - frontiersin.org
The development of digital cancer twins relies on the capture of high-resolution
representations of individual cancer patients throughout the course of their treatment. Our …

Printed electrochemical strip for the detection of miRNA-29a: a possible biomarker related to Alzheimer's disease

A Miglione, A Raucci, J Amato, S Marzano… - Analytical …, 2022 - ACS Publications
The development of electrochemical strips, as extremely powerful diagnostic tools, has
received much attention in the field of sensor analysis and, in particular, the detection of …

The potential of DNA methylation as a biomarker for obesity and smoking

A Heikkinen, S Bollepalli… - Journal of internal …, 2022 - Wiley Online Library
DNA methylation is an epigenetic modification that has consistently been shown to be linked
with a variety of human traits and diseases. Because DNA methylation is dynamic and …

Mechanisms of DNA methylation and histone modifications

S Acharjee, S Chauhan, R Pal, RS Tomar - Progress in molecular biology …, 2023 - Elsevier
The field of genetics has expanded a lot in the past few decades due to the accessibility of
human genome sequences, but still, the regulation of transcription cannot be explicated …

Identification of epigenetic interactions between MicroRNA-30c-5p and DNA methyltransferases in neuropathic pain

R Francés, J Mata-Garrido, R de la Fuente… - International Journal of …, 2022 - mdpi.com
Neuropathic pain is a prevalent and severe chronic syndrome, often refractory to treatment,
whose development and maintenance may involve epigenetic mechanisms. We previously …

Methylation and noncoding RNAs in gastric cancer: everything is connected

IV Bure, MV Nemtsova - International journal of molecular sciences, 2021 - mdpi.com
Despite recent progress, gastric cancer remains one of the most common cancers and has a
high mortality rate worldwide. Aberrant DNA methylation pattern and deregulation of …

Precision oncology: artificial intelligence and DNA methylation analysis of circulating cell-free DNA for lung cancer detection

R Bahado-Singh, KT Vlachos, B Aydas… - Frontiers in …, 2022 - frontiersin.org
Background Lung cancer (LC) is a leading cause of cancer-deaths globally. Its lethality is
due in large part to the paucity of accurate screening markers. Precision Medicine includes …