The world is engulfed by one of the most widespread and significant public health crises in
decades as COVID-19 has become among the leading causes of death internationally. The …

The kidney harbours different types of endothelia, each with specific structural and functional
characteristics. The glomerular endothelium, which is highly fenestrated and covered by a …

The complement cascade, traditionally considered an effector arm of innate immunity
required for host defense against pathogens, is now recognized as a crucial pathogenic …

Atypical hemolytic-uremic syndrome (aHUS) is associated with genetic complement
abnormalities/anti–complement factor H antibodies, which paved the way to treatment with …

Hemolytic uremic syndrome (HUS) is a triad of microangiopathic hemolytic anemia,
thrombocytopenia, and acute renal failure. The atypical form of HUS is a disease …

In the past decade, a large body of evidence has accumulated in support of the critical role
of dysregulation of the alternative complement pathway in atypical haemolytic uraemic …

Hemolytic uremic syndrome (HUS) is defined by the triad of mechanical hemolytic anemia,
thrombocytopenia and renal impairment. Atypical HUS (aHUS) defines non Shiga-toxin …

Introduction Thrombotic microangiopathy (TMA) is a life-threatening, albeit infrequent,
complication of systemic lupus erythematosus (SLE) and anti-phospholipid syndrome (APS) …

Haemolytic uraemic syndrome (HUS) is defined by the simultaneous occurrence of
nonimmune haemolytic anaemia, thrombocytopenia and acute renal failure. This leads to …

Hemolytic uremic syndrome (HUS) is a thrombotic microangiopathy defined by
thrombocytopenia, nonimmune microangiopathic hemolytic anemia, and acute renal failure …