Lack of an effective drug therapy for abdominal aortic aneurysm
Abdominal aortic aneurysm (AAA) rupture is a common cause of death in adults. Current
AAA treatment is by open surgical or endovascular aneurysm repair. Rodent model and …
AAA treatment is by open surgical or endovascular aneurysm repair. Rodent model and …
The gut microbiome and cardiovascular disease: current knowledge and clinical potential
AF Ahmad, G Dwivedi, F O'Gara… - American Journal …, 2019 - journals.physiology.org
Cardiovascular disease (CVD) is the leading cause of death worldwide. The human body is
populated by a diverse community of microbes, dominated by bacteria, but also including …
populated by a diverse community of microbes, dominated by bacteria, but also including …
Atherosclerosis and abdominal aortic aneurysm: cause, response, or common risk factors?
J Golledge, PE Norman - Arteriosclerosis, thrombosis, and …, 2010 - Am Heart Assoc
Abdominal aortic aneurysm (AAA) rupture has been recognized as a significant cause of
mortality for adults aged 60 years in the developed world for some time. 1 AAAs are usually …
mortality for adults aged 60 years in the developed world for some time. 1 AAAs are usually …
[HTML][HTML] Challenges and opportunities in limiting abdominal aortic aneurysm growth
J Golledge, PE Norman, MP Murphy… - Journal of vascular …, 2017 - Elsevier
Objective This review describes ongoing efforts to develop a medical therapy to limit
abdominal aortic aneurysm (AAA) growth. Methods Data from animal model studies, human …
abdominal aortic aneurysm (AAA) growth. Methods Data from animal model studies, human …
Oxidative stress and inflammatory markers in abdominal aortic aneurysm
D Sánchez-Infantes, M Nus, M Navas-Madroñal, J Fité… - Antioxidants, 2021 - mdpi.com
Abdominal aortic aneurysm (AAA) is increasing due to aging of the population and is a
major cause of death among the elderly. Ultrasound screening programs are useful in early …
major cause of death among the elderly. Ultrasound screening programs are useful in early …
Diagnosis and monitoring of abdominal aortic aneurysm: current status and future prospects
Abdominal aortic aneurysm (AAA) remains an important cause of morbidity and mortality in
elderly men, and prevalence is predicted to increase in parallel with a global aging …
elderly men, and prevalence is predicted to increase in parallel with a global aging …
Oxidative stress and abdominal aortic aneurysm: potential treatment targets
Abdominal aortic aneurysm (AAA) is a significant cause of mortality in older adults. A key
mechanism implicated in AAA pathogenesis is inflammation and the associated production …
mechanism implicated in AAA pathogenesis is inflammation and the associated production …
Prevention of CaCl2-induced aortic inflammation and subsequent aneurysm formation by the CCL3–CCR5 axis
Y Ishida, Y Kuninaka, M Nosaka, A Kimura… - Nature …, 2020 - nature.com
Inflammatory mediators such as cytokines and chemokines are crucially involved in the
development of abdominal aortic aneurysm (AAA). Here we report that CaCl2 application …
development of abdominal aortic aneurysm (AAA). Here we report that CaCl2 application …
Animal models of abdominal aortic aneurysm and their role in furthering management of human disease
Abdominal aortic aneurysm is a common degenerative disorder associated with sudden
death due to aortic rupture. Current therapy is limited to open surgical repair of the aorta or …
death due to aortic rupture. Current therapy is limited to open surgical repair of the aorta or …
Repair of Abdominal Aortic Aneurysms: JACC Focus Seminar, Part 1
SE Hensley, GR Upchurch Jr - Journal of the American College of …, 2022 - jacc.org
Abdominal aortic aneurysms (AAAs), defined by an aortic diameter> 3 cm, affect> 1 million
people in the United States. Risk factors for AAA include male sex, family history of AAA …
people in the United States. Risk factors for AAA include male sex, family history of AAA …