Colorectal cancer biology, diagnosis, and therapeutic approaches

B Dariya, S Aliya, N Merchant, A Alam… - Critical Reviews™ in …, 2020 - dl.begellhouse.com
Colorectal cancer (CRC) is the second most diagnosed disease worldwide. It is the fourth
leading cause of cancer related mortalities. Higher probability for the occurrence of CRC is …

[HTML][HTML] New trends in the therapeutic approach to metastatic colorectal cancer

J Sánchez-Gundín… - … journal of medical …, 2018 - ncbi.nlm.nih.gov
Important developments in chemotherapy for metastatic colorectal cancer over the last years
are reviewed, with an emphasis on the most recently published data from clinical trials. The …

[HTML][HTML] Omega-3 PUFA loaded in resveratrol-based solid lipid nanoparticles: physicochemical properties and antineoplastic activities in human colorectal cancer …

S Serini, R Cassano, PA Corsetto, AM Rizzo… - International journal of …, 2018 - mdpi.com
New strategies are being investigated to ameliorate the efficacy and reduce the toxicity of
the drugs currently used in colorectal cancer (CRC), one of the most common malignancies …

[HTML][HTML] Management of adverse events during treatment of gastrointestinal cancers with epidermal growth factor inhibitors

RD Hofheinz, S Segaert, MJ Safont, G Demonty… - Critical Reviews in …, 2017 - Elsevier
The epidermal growth factor receptor (EGFR) is involved in development and progression of
some gastrointestinal cancers, and is targeted by monoclonal antibodies (mAbs) and …

[HTML][HTML] The Impact of Bevacizumab and Chemotherapy on Quality of Life in Metastatic Colorectal Cancer Patients

DC Moisuc, MV Marinca, AM Matei, L Popovici… - Healthcare, 2023 - mdpi.com
Health-related quality is of life of great importance in cancer care. This prospective study
aimed to evaluate the impact of chemotherapy and bevacizumab on the activities of daily …

[HTML][HTML] Turkish validation and reliability of the EORTC QLQ-CR29 quality of life scale for colorectal cancer

F Akduran, Z Durna - The Turkish Journal of Gastroenterology, 2021 - ncbi.nlm.nih.gov
Background This study aims to test the validity and reliability of the Turkish version of the
European Organization for Research and Treatment of Cancer, Quality of Life Questionnaire …

Kolorektal kanserli hastalarda yaşam kalitesinin değerlendirilmesi

F Akduran - 2015 - acikerisim.demiroglu.bilim.edu.tr
Bu araştırma “Kolorektal Kanserli Hastalarda Yaşam Kalitesi”(KKHYK)[European
Organisation for Research and Treatment of Cancer, Quality of Life Questionnaire …

A snapshot of challenges and solutions in cancer drug development and therapy

MA Phelps, A Sparreboom - Clinical Pharmacology & …, 2014 - Wiley Online Library
Cancer chemotherapy has transitioned from the use of cytotoxic drugs to the era of agents
with an apparent selectivity for a cancer‐specific target. The past decade has provided …

Basics of polypharmacology

Z Wang, B Yang - Polypharmacology: Principles and methodologies, 2022 - Springer
Polypharmacology is frequently referred to the design or use of pharmaceutical agents that
act on multiple molecular targets or multiple signaling pathways for multifactorial human …

Health-related quality of life related to toxicity treatments in central nervous system metastases

T Walbert, ES Horta - Central Nervous System Metastases, 2020 - Springer
Health-related quality of life (HRQoL) is a multidimensional concept that measures how a
disease and the treatment of that disease impact a patient's life. It can also aid in the …