[HTML][HTML] Epigenetic modification of gene expression in cancer cells by terahertz demethylation
Terahertz (THz) radiation can affect the degree of DNA methylation, the spectral
characteristics of which exist in the terahertz region. DNA methylation is an epigenetic …
characteristics of which exist in the terahertz region. DNA methylation is an epigenetic …
[HTML][HTML] Epigenetics and cancer
Epigenetic modifications are central to many human diseases, including cancer.
Traditionally, cancer has been viewed as a genetic disease, and it is now becoming …
Traditionally, cancer has been viewed as a genetic disease, and it is now becoming …
Neural tube defects and folate pathway genes: family-based association tests of gene–gene and gene–environment interactions
AL Boyles, AV Billups, KL Deak… - Environmental …, 2006 - ehp.niehs.nih.gov
Background Folate metabolism pathway genes have been examined for association with
neural tube defects (NTDs) because folic acid supplementation reduces the risk of this …
neural tube defects (NTDs) because folic acid supplementation reduces the risk of this …
Genome wide DNA methylation profiling for epigenetic alteration in coronary artery disease patients
Background The alteration in the epigenome forms an interface between the genotype and
the environment. Epigenetic alteration is expected to make a significant contribution to the …
the environment. Epigenetic alteration is expected to make a significant contribution to the …
Integrated analysis of DNA methylation and mRNA expression profiling reveals candidate genes associated with cisplatin resistance in non-small cell lung cancer
YW Zhang, Y Zheng, JZ Wang, XX Lu, Z Wang… - Epigenetics, 2014 - Taylor & Francis
DNA methylation plays a critical role during the development of acquired chemoresistance.
The aim of this study was to identify candidate DNA methylation drivers of cisplatin (DDP) …
The aim of this study was to identify candidate DNA methylation drivers of cisplatin (DDP) …
TGF-β signaling controls Foxp3 methylation and T reg cell differentiation by modulating Uhrf1 activity
X Sun, Y Cui, H Feng, H Liu, X Liu - Journal of Experimental Medicine, 2019 - rupress.org
Regulatory T (T reg) cells are required for the maintenance of immune homeostasis. Both
TGF-β signaling and epigenetic modifications are important for Foxp3 induction, but how …
TGF-β signaling and epigenetic modifications are important for Foxp3 induction, but how …
Polymorphisms in folate metabolism genes as maternal risk factor for neural tube defects: an updated meta-analysis
U Yadav, P Kumar, SK Yadav, OP Mishra, V Rai - Metabolic brain disease, 2015 - Springer
Epidemiological studies have evaluated the association between maternal
methylenetetrahydrofolate reductase (MTHFR) C677T, A1298C and methionine synthase …
methylenetetrahydrofolate reductase (MTHFR) C677T, A1298C and methionine synthase …
Maternal fumonisin exposure as a risk factor for neural tube defects
J Gelineau‐van Waes, KA Voss, VL Stevens… - Advances in food and …, 2009 - Elsevier
Fumonisins are mycotoxins produced by the fungus F. verticillioides, a common contaminant
of maize (corn) worldwide. Maternal consumption of fumonisin B 1‐contaminated maize …
of maize (corn) worldwide. Maternal consumption of fumonisin B 1‐contaminated maize …
[HTML][HTML] Therapeutic modulation of gene expression in the disease state: Treatment strategies and approaches for the development of next-generation of the …
J Rittiner, M Cumaran, S Malhotra… - … in Bioengineering and …, 2022 - frontiersin.org
Epigenetic dysregulation is an important determinant of many pathological conditions and
diseases. Designer molecules that can specifically target endogenous DNA sequences …
diseases. Designer molecules that can specifically target endogenous DNA sequences …
[HTML][HTML] A distinct DNA-methylation boundary in the 5′-upstream sequence of the FMR1 promoter binds nuclear proteins and is lost in fragile X syndrome
A Naumann, N Hochstein, S Weber, E Fanning… - The American Journal of …, 2009 - cell.com
We have discovered a distinct DNA-methylation boundary at a site between 650 and 800
nucleotides upstream of the CGG repeat in the first exon of the human FMR1 gene. This …
nucleotides upstream of the CGG repeat in the first exon of the human FMR1 gene. This …