Functions and mechanisms of epigenetic inheritance in animals
The idea that epigenetic determinants such as DNA methylation, histone modifications or
RNA can be passed to the next generation through meiotic products (gametes) is long …
RNA can be passed to the next generation through meiotic products (gametes) is long …
DNA methylation landscapes: provocative insights from epigenomics
MM Suzuki, A Bird - Nature reviews genetics, 2008 - nature.com
The genomes of many animals, plants and fungi are tagged by methylation of DNA cytosine.
To understand the biological significance of this epigenetic mark it is essential to know …
To understand the biological significance of this epigenetic mark it is essential to know …
DNA methylation patterns and epigenetic memory
A Bird - Genes & development, 2002 - genesdev.cshlp.org
The character of a cell is defined by its constituent proteins, which are the result of specific
patterns of gene expression. Crucial determinants of gene expression patterns are DNA …
patterns of gene expression. Crucial determinants of gene expression patterns are DNA …
[HTML][HTML] Sperm, but not oocyte, DNA methylome is inherited by zebrafish early embryos
methylcytosine is a major epigenetic modification that is sometimes called" the fifth
nucleotide." However, our knowledge of how offspring inherit the DNA methylome from …
nucleotide." However, our knowledge of how offspring inherit the DNA methylome from …
Epigenetic modification and inheritance in sexual reversal of fish
Environmental sex determination (ESD) occurs in divergent, phylogenetically unrelated taxa,
and in some species, co-occurs with genetic sex determination (GSD) mechanisms …
and in some species, co-occurs with genetic sex determination (GSD) mechanisms …
Epigenetic reprogramming in mammalian development
DNA methylation is a major epigenetic modification of the genome that regulates crucial
aspects of its function. Genomic methylation patterns in somatic differentiated cells are …
aspects of its function. Genomic methylation patterns in somatic differentiated cells are …
Genomic imprinting: parental influence on the genome
Genomic imprinting affects several dozen mammalian genes and results in the expression of
those genes from only one of the two parental chromosomes. This is brought about by …
those genes from only one of the two parental chromosomes. This is brought about by …
Epigenetics as a unifying principle in the aetiology of complex traits and diseases
A Petronis - Nature, 2010 - nature.com
Epigenetic modifications of DNA and histones might be crucial for understanding the
molecular basis of complex phenotypes. One reason for this is that epigenetic factors are …
molecular basis of complex phenotypes. One reason for this is that epigenetic factors are …
[HTML][HTML] Reprogramming the maternal zebrafish genome after fertilization to match the paternal methylation pattern
ME Potok, DA Nix, TJ Parnell, BR Cairns - Cell, 2013 - cell.com
Early vertebrate embryos must achieve totipotency and prepare for zygotic genome
activation (ZGA). To understand this process, we determined the DNA methylation (DNAme) …
activation (ZGA). To understand this process, we determined the DNA methylation (DNAme) …
Inherited epigenetic variation—revisiting soft inheritance
EJ Richards - Nature Reviews Genetics, 2006 - nature.com
Phenotypic variation is traditionally parsed into components that are directed by genetic and
environmental variation. The line between these two components is blurred by inherited …
environmental variation. The line between these two components is blurred by inherited …