The idea that epigenetic determinants such as DNA methylation, histone modifications or
RNA can be passed to the next generation through meiotic products (gametes) is long …

The genomes of many animals, plants and fungi are tagged by methylation of DNA cytosine.
To understand the biological significance of this epigenetic mark it is essential to know …

The character of a cell is defined by its constituent proteins, which are the result of specific
patterns of gene expression. Crucial determinants of gene expression patterns are DNA …

methylcytosine is a major epigenetic modification that is sometimes called" the fifth
nucleotide." However, our knowledge of how offspring inherit the DNA methylome from …

Environmental sex determination (ESD) occurs in divergent, phylogenetically unrelated taxa,
and in some species, co-occurs with genetic sex determination (GSD) mechanisms …

DNA methylation is a major epigenetic modification of the genome that regulates crucial
aspects of its function. Genomic methylation patterns in somatic differentiated cells are …

Genomic imprinting affects several dozen mammalian genes and results in the expression of
those genes from only one of the two parental chromosomes. This is brought about by …

Epigenetic modifications of DNA and histones might be crucial for understanding the
molecular basis of complex phenotypes. One reason for this is that epigenetic factors are …

Early vertebrate embryos must achieve totipotency and prepare for zygotic genome
activation (ZGA). To understand this process, we determined the DNA methylation (DNAme) …

Phenotypic variation is traditionally parsed into components that are directed by genetic and
environmental variation. The line between these two components is blurred by inherited …