Normal brain function requires a tightly regulated balance between excitatory and inhibitory
neurotransmissions. γ‐Aminobutyric acid type A (GABAA) receptors represent the major …

Abstract Purpose of Review Patients with acute neurologic injury require a specialized
approach to critical care, particularly with regard to sedation and analgesia. This article …

This study aimed to investigate the anticonvulsant effects of citronellal (CIT) and possible
underlying mechanisms through an isoniazid (INH)-induced seizure (convulsion) via in vivo …

Abstract Background and Objectives Over the last decade, significant advancements have
been made in status epilepticus (SE) management, influenced by landmark trials such as …

Background Antiseizure medication (ASM) as monotherapy or in combination is the
treatment of choice for most patients with epilepsy. Therefore, knowledge about the typical …

Background Multiple studies have focused on medical and pharmacological treatments and
outcome predictors of patients with status epilepticus (SE). However, a sufficient …

Orally administered antipsychotic drugs are the first-line treatment for psychotic disorders,
such as schizophrenia and bipolar disorder. Nevertheless, adverse drug reactions …

Biological activities require a delicate balance between excitatory and inhibitory signals in
the brain. Disruption of this balance could lead to neurological disorders, such as …

In this work, a novel benzodiazepine-2-one derivative (4) was synthesized by N-allylation of
cyclopenta [e][1, 5] benzodiazepine-2-one. The chemical structure of the target compound …

Patients with epilepsy may experience seizure clusters, which are described by the US Food
and Drug Administration (FDA) as intermittent, stereotypic episodes of frequent seizure …