Diarrhea is one of the main drawbacks for cancer patients. Possible etiologies could be
radiotherapy, chemotherapeutic agents, decreased physical performance, graft versus host …

Diarrhoea is a common, debilitating and potentially life threatening toxicity of many cancer
therapies. While the mechanisms of diarrhoea induced by traditional chemotherapy have …

Aim The aim of the study was to analyse the prevalence and characteristics of secondary
diabetes induced by 5‐fluorouracil (5‐FU) based chemotherapy in non‐diabetic patients …

Purpose of research Revision of the literature on targeted therapy-induced diarrhea (TT-ID).
Principal results TT-ID is frequent; the mechanisms are mainly secretive, followed by …

Objectives This analysis was conducted to clarify risk factors for severe adverse effects and
treatment-related deaths reported during a postmarketing survey of irinotecan. Methods The …

Cancer therapeutic methods comprising chemotherapy, radiotherapy, and surgery are so
routine in cancer treatment. Remarkably, there are several personal features which affect the …

Chemotherapy-induced diarrhea (CID) is a common, severe side effect of chemotherapy,
immunotherapy, and targeted therapy. Because patients are more prone to continuing …

Anti-cancer drugs generally target cancer cells rather than normal somatic cells. However,
the factors that determine this differential sensitivity are poorly understood. Here we show …

Fluorouracil (5-FU) is a “cytotoxic” drug used for cancer chemotherapy, which inhibits cells
division via affecting DNA synthesis. Although being widely used for cancer treatment, 5-FU …

Fluorouracil (5-FU) is widely used as an anti cancer drug and is known to cause severe
diarrhea. Recently we suggested that levels of chemokine (CXC motif) ligand 1 (CXCL1) …