Liver cancer is the fifth most common cancer and the second leading cause of malignant
death in Asia, and Asia reports 72.5% of the world's cases in 2020. As the most common …

Inflammation, especially chronic inflammation, plays a pivotal role in tumorigenesis and
metastasis through various mechanisms and is now recognized as a hallmark of cancer and …

Hepatocellular carcinoma (HCC) is one of the major causes of cancer-related death.
Although the burden of alcohol-and NASH-related HCC is growing, chronic viral hepatitis …

Insulin-like Growth Factor (IGF)/IGF-1 Receptor (IGF-1R) signaling is known to regulate stem
cell pluripotency and differentiation to trigger cell proliferation, organ development, and …

Hepatocellular carcinoma (HCC), is the third leading cause of cancer-related deaths, which
is largely caused by virus infection. About 80% of the virus-infected people develop a …

Chronic hepatitis C virus (HCV) infection induces liver inflammation that can lead to fibrosis,
cirrhosis, and hepatocellular carcinoma (HCC). Inflammation is the outcome of the action of …

The pathogenesis of hepatocellular carcinoma (HCC) is a multifactorial process that has not
yet been fully investigated. Autophagy and apoptosis are two important cellular pathways …

Background: Hepatitis B-related liver cirrhosis (HBV-LC) is a common clinical disease that
evolves from chronic hepatitis B (CHB). The development of cirrhosis can be suppressed by …

The gut–liver-axis is a bidirectional coordination between the gut, including microbial
residents, the gut microbiota, from one side and the liver on the other side. Any disturbance …

Liver cancer is a leading cause of cancer-related mortality globally. Since hepatitis virus
infections have been strongly associated with the incidence of liver cancer, studies …