Brain organoids are derived from induced pluripotent stem cells and embryonic stem cells
under 3-dimensional culture condition. The generation of organoid requires the self …

Drinking alcohol, even in moderation, can affect the immune system. Studies have shown
disproportionate effects of alcohol on circulating and tissue-resident myeloid cells …

The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the causative
agent of coronavirus disease 2019 (COVID-19), which was rapidly declared a pandemic by …

Reciprocal deletion and duplication of the 16p11. 2 region is the most common copy number
variation (CNV) associated with autism spectrum disorders. We generated cortical organoids …

Prenatal alcohol exposure is the foremost preventable etiology of intellectual disability and
leads to a collection of diagnoses known as Fetal Alcohol Spectrum Disorders (FASD) …

Advances in the field of human stem cells are often a source of public and ethical
controversy. Researchers must frequently balance diverse societal perspectives on …

The achievement of an HIV cure is dependent on the eradication or permanent silencing of
HIV-latent viral reservoirs, including the understudied central nervous system (CNS) …

Psychiatric disorders are often distinguished from neurological disorders in that the former
do not have characteristic lesions or findings from cerebrospinal fluid …

Understanding of human brain development, dysfunction and neurological diseases has
remained limited and challenging due to inability to recapitulate human brain-specific …

Brain organoids are three-dimensional (3D) structures derived from human pluripotent stem
cells (hPSCs) that reflect early brain organization. These organoids contain different cell …