Over the past few decades, DNA methylation at the 5-position of cytosine (5-methylcytosine,
5mC) has emerged as an important epigenetic modification that plays essential roles in …

Early biochemical experiments established that the set of dinucleotide odds ratios or
'general design'is a remarkably stable property of the DNA of an organism, which is …

Summary Ten-Eleven Translocation (Tet) family of dioxygenases dynamically regulates
DNA methylation and has been implicated in cell lineage differentiation and oncogenesis …

Regulatory T cells play important roles in the control of autoimmunity and maintenance of
transplantation tolerance. Foxp3, a member of the forkhead/winged-helix family of …

▪ Abstract Methylation of cytosine residues in DNA provides a mechanism of gene control.
There are two classes of methyltransferase in Arabidopsis; one has a carboxy-terminal …

Dinucleotide over-and underrepresentation is evaluated in all available completely
sequenced DNA or RNA viral genomes, ranging in size from 3 to 250 kb (available RNA …

Structure and Function of DNA Methyltransferases Page 1 Annu. Rev. Biophys. Biomol. Struct.
1995.24:293-318 Copyright © 1995 by Annual Reviews Inc. All rights reserved STRUCTURE …

Gene silencing in transgenic plants has emerged in the last 5 years as a topic of intense
interest for both applied and basic plant scientists. From the applied side, gene silencing has …

Programmed methylation and demethylation of regulatory sequences has been proposed to
play a central role in vertebrate development. We report here that the methylation status of …

Stem cells and multipotent progenitor cells face the challenge of balancing the stability and
plasticity of their developmental states. Their self-renewal requires the maintenance of a …