The tools for virulence of Cryptococcus neoformans
Cryptococcus neoformans is a fungal pathogen that causes almost half a million deaths
each year. It is believed that most humans are infected with C. neoformans, possibly in a …
each year. It is believed that most humans are infected with C. neoformans, possibly in a …
Regulatory and pathogenic mechanisms in response to iron deficiency and excess in fungi
J Pijuan, DF Moreno, G Yahya, M Moisa… - Microbial …, 2023 - Wiley Online Library
Iron is an essential element for all eukaryote organisms because of its redox properties,
which are important for many biological processes such as DNA synthesis, mitochondrial …
which are important for many biological processes such as DNA synthesis, mitochondrial …
A nonribosomal peptide synthetase mediates siderophore production and virulence in the citrus fungal pathogen Alternaria alternata
A lternaria species produce and excrete dimethyl coprogen siderophores to acquire iron.
The A lternaria alternata gene AaNPS6, encoding a polypeptide analogous to fungal …
The A lternaria alternata gene AaNPS6, encoding a polypeptide analogous to fungal …
Metabolic Plasticity of Candida albicans in Response to Different Environmental Conditions
M Gallo, L Giovati, W Magliani, TA Pertinhez, S Conti… - Journal of Fungi, 2022 - mdpi.com
The ubiquitous commensal Candida albicans, part of the human microbiota, is an
opportunistic pathogen able to cause a wide range of diseases, from cutaneous mycoses to …
opportunistic pathogen able to cause a wide range of diseases, from cutaneous mycoses to …
An encapsulation of iron homeostasis and virulence in Cryptococcus neoformans
JW Kronstad, G Hu, WH Jung - Trends in microbiology, 2013 - cell.com
Vertebrate hosts actively sequester iron, and fungal and other pathogens must therefore
adapt to a severe limitation in iron availability to cause disease. Recent studies reveal that …
adapt to a severe limitation in iron availability to cause disease. Recent studies reveal that …
Strategies of intracellular pathogens for obtaining iron from the environment
N Leon-Sicairos, R Reyes-Cortes… - BioMed research …, 2015 - Wiley Online Library
Most microorganisms are destroyed by the host tissues through processes that usually
involve phagocytosis and lysosomal disruption. However, some organisms, called …
involve phagocytosis and lysosomal disruption. However, some organisms, called …
Mycotoxin biosynthesis and central metabolism are two interlinked pathways in Fusarium graminearum, as demonstrated by the extensive metabolic changes induced …
V Atanasova-Penichon, L Legoahec… - Applied and …, 2018 - Am Soc Microbiol
Fusarium graminearum is a major plant pathogen that causes devastating diseases of
cereals and produces type B trichothecene (TCTB) mycotoxins in infected grains. A …
cereals and produces type B trichothecene (TCTB) mycotoxins in infected grains. A …
Systems biology approaches for host–fungal interactions: An expanding multi-omics frontier
L Culibrk, CA Croft, SJ Tebbutt - OMICS: A Journal of Integrative …, 2016 - liebertpub.com
Opportunistic fungal infections are an increasing threat for global health, and for
immunocompromised patients in particular. These infections are characterized by interaction …
immunocompromised patients in particular. These infections are characterized by interaction …
Catch the wave: metabolomic analyses in human pathogenic fungi
P Brandt, E Garbe, S Vylkova - Advances in Clinical Immunology …, 2021 - taylorfrancis.com
One key biological application of metabolomics is the identification of disease signatures
and biomarkers. The routine measurement of single molecules or a pattern of several …
and biomarkers. The routine measurement of single molecules or a pattern of several …
Siderophore Biosynthesis but Not Reductive Iron Assimilation Is Essential for the Dimorphic Fungus Nomuraea rileyi Conidiation, Dimorphism Transition, Resistance …
Y Li, Z Wang, X Liu, Z Song, R Li, C Shao… - Frontiers in …, 2016 - frontiersin.org
Iron is an indispensable factor for the dimorphic insect pathogenic Nomuraea rileyi to form
persistent microsclerotia which can replace conidia or blastospores for commercial mass …
persistent microsclerotia which can replace conidia or blastospores for commercial mass …