Global analysis of cytosine and adenine DNA modifications across the tree of life

SJ Varma, E Calvani, NM Grüning, CB Messner… - Elife, 2022 - elifesciences.org
Interpreting the function and metabolism of enzymatic DNA modifications requires both
position-specific and global quantities. Sequencing-based techniques that deliver the former …

Transcribed ultraconserved regions in cancer

MK Gibert Jr, A Sarkar, B Chagari, C Roig-Laboy… - Cells, 2022 - mdpi.com
Transcribed ultraconserved regions are putative lncRNA molecules that are transcribed from
DNA that is 100% conserved in human, mouse, and rat genomes. This is notable, as …

The mitochondrial genome and Epigenome of the Golden lion Tamarin from fecal DNA using Nanopore adaptive sequencing

N Wanner, PA Larsen, A McLain, C Faulk - BMC genomics, 2021 - Springer
Background The golden lion tamarin (Leontopithecus rosalia) is an endangered Platyrrhine
primate endemic to the Atlantic coastal forests of Brazil. Despite ongoing conservation …

Developmental cannabidiol exposure increases anxiety and modifies genome-wide brain DNA methylation in adult female mice

NM Wanner, M Colwell, C Drown, C Faulk - Clinical epigenetics, 2021 - Springer
Background Use of cannabidiol (CBD), the primary non-psychoactive compound found in
cannabis, has recently risen dramatically, while relatively little is known about the underlying …

Bisphenol A-associated alterations in DNA and histone methylation affects semen quality in rare minnow Gobiocypris rarus

L Zhu, C Yuan, M Wang, Y Liu, Z Wang, MM Seif - Aquatic Toxicology, 2020 - Elsevier
Bisphenol A (BPA), a well-known estrogenic endocrine disruptor, is ubiquitously present in
the environment, possessing the potential to interfere with the reproductive endocrine …

[HTML][HTML] The evolution of CpG density and lifespan in conserved primate and mammalian promoters

AT McLain, C Faulk - Aging (Albany NY), 2018 - ncbi.nlm.nih.gov
Gene promoters are evolutionarily conserved across holozoans and enriched in CpG sites,
the target for DNA methylation. As animals age, the epigenetic pattern of DNA methylation …

The epigenetic machinery in the life cycle and pharmacoepigenetics

R Cacabelos, I Tellado, P Cacabelos - Pharmacoepigenetics, 2019 - Elsevier
Epigenetics is a discipline that studies potentially reversible heritable changes in gene
expression with no structural modifications in the DNA sequence. The epigenetic machinery …

Sequencing Bait: Nuclear and Mitogenome Assembly of an Abundant Coastal Tropical and Subtropical Fish, Atherinomorus stipes

MK Drown, AN DeLiberto, N Flack… - Genome biology and …, 2022 - academic.oup.com
Genetic data from nonmodel species can inform ecology and physiology, giving insight into
a species' distribution and abundance as well as their responses to changing environments …

Emerging DNA methylation inhibitors for cancer therapy: challenges and prospects

A Gonzalez-Fierro… - Expert Review of …, 2019 - Taylor & Francis
Introduction: There is evidence of the association of DNA methylation alterations with cancer
development and progression. Areas covered: This review will briefly discuss the basis of …

Association of DNA methylation with energy and fear-related behaviors in canines

AR Sanders, N Bhongir, B vonHoldt… - Frontiers in …, 2022 - frontiersin.org
Introduction Behavioral traits are influenced by gene by environment interactions. To study
the genetic and epigenetic components of behavior, we analyzed whether dog behavioral …