The role of epigenetic mechanisms in the regulation of gene expression in the cyclical endometrium

AM Retis-Resendiz, IN González-García… - Clinical …, 2021 - Springer
Background The human endometrium is a highly dynamic tissue whose function is mainly
regulated by the ovarian steroid hormones estradiol and progesterone. The serum levels of …

Epigenetic modifications working in the decidualization and endometrial receptivity

H Liu, X Huang, G Mor, A Liao - Cellular and Molecular Life Sciences, 2020 - Springer
Decidualization is a critical event for the blastocyst implantation, placental development and
fetal growth and the normal term. In mice, the embryo implantation to the uterine epithelial …

The role of long non-coding RNA H19 in infertility

Y Peng, R Guo, B Shi, D Li - Cell Death Discovery, 2023 - nature.com
Infertility is defined as the failure to conceive after at least one year of unprotected
intercourse. Long non-coding RNAs (lncRNAs) are transcripts that contain more than 200 …

[HTML][HTML] Construction of implantation failure related lncRNA-mRNA network and identification of lncRNA biomarkers for predicting endometrial receptivity

C Feng, JM Shen, PP Lv, M Jin, LQ Wang… - … journal of biological …, 2018 - ncbi.nlm.nih.gov
Insufficient endometrial receptivity is a major factor leading to implantation failure (IF), and
the traditional way of morphological observation of endometrium cannot determine the …

Genome-wide analysis of long noncoding RNAs, microRNAs, and mRNAs forming a competing endogenous RNA network in repeated implantation failure

H Xu, M Zhou, YI Cao, DAN Zhang, MI Han, X Gao… - Gene, 2019 - Elsevier
Repeated implantation failure (RIF) was mainly due to poor endometrium receptivity. Long
noncoding RNAs (lncRNAs) could regulate endometrium receptivity and act in competing …

A novel molecule in human cyclic endometrium: LncRNA TUNAR is involved in embryo implantation

Y Wang, S Hu, G Yao, Q Zhu, Y He, Y Lu, J Qi… - Frontiers in …, 2020 - frontiersin.org
Embryo implantation rate remains an inefficient process in in vitro fertilization and embryo
transfer (IVF-ET) cycles. The role long non-coding RNA (lncRNA) plays in embryo …

H19 regulates trophoblastic spheroid adhesion by competitively binding to let-7

D He, H Zeng, J Chen, L Xiao, Y Zhao, N Liu - Reproduction, 2019 - rep.bioscientifica.com
Integrin β3 (ITGB3), which is the target gene of the miRNA let-7 that can be antagonized by
long noncoding RNA (lncRNA) H19, is well-known to have a critical role in endometrium …

H19 regulates angiogenic capacity of extravillous trophoblasts by H19/miR-106a-5p/VEGFA axis

H Zeng, D He, H Xie, Y Zhao, Z Peng, H Deng… - Archives of Gynecology …, 2020 - Springer
Purpose To investigate the role and underlying mechanism of H19 in regulating angiogenic
capacity of extravillous trophoblasts. Methods Gain and loss of function experiments were …

[HTML][HTML] 非编码RNA 调控哺乳动物子宫内膜容受性和蜕膜化的研究进展

秦雪, 沙懿文, 杨梦豪, 蔡瑞, 庞卫军 - 畜牧兽医学报, 2023 - xml-data.org
子宫内膜容受性和蜕膜化作为胚胎附植的重要环节, 影响哺乳动物的成功妊娠和繁殖性能,
所以探究子宫生理功能的调控机制对提高母畜繁殖率具有重要意义. 子宫内膜容受性是指子宫内 …

LINC02190 inhibits the embryo–endometrial attachment by decreasing ITGAD expression

F Zhao, T Chen, X Zhao, Q Wang, Y Lan… - …, 2022 - rep.bioscientifica.com
Recurrent implantation failure (RIF) is a challenge in the field of reproductive medicine, but
mechanisms for its occurrence remain still unclear. Long non-coding RNAs (lncRNAs) have …