[HTML][HTML] Identification of the risk genes associated with vulnerability to addiction: Major findings from transgenic animals

CJ Jordan, ZX Xi - Frontiers in Neuroscience, 2022 - frontiersin.org
Understanding risk factors for substance use disorders (SUD) can facilitate medication
development for SUD treatment. While a rich literature exists discussing environmental …

Prenatal effects of nicotine on obesity risks: a narrative review

O White, N Roeder, K Blum, RD Eiden… - International journal of …, 2022 - mdpi.com
Nicotine usage by mothers throughout pregnancy has been observed to relate to numerous
deleterious effects in children, especially relating to obesity. Children who have prenatally …

Should reward deficiency syndrome (RDS) be considered an umbrella disorder for mental illness and associated genetic and epigenetic induced dysregulation of …

K Blum, CA Dennen, I Elman, A Bowirrat… - Journal of Personalized …, 2022 - mdpi.com
Reward Deficiency Syndrome (RDS) is defined as a breakdown of reward
neurotransmission that results in a wide range of addictive, compulsive, and impulsive …

Researching mitigation of alcohol binge drinking in polydrug abuse: KCNK13 and RASGRF2 Gene (s) Risk Polymorphisms Coupled with Genetic Addiction Risk …

K Blum, MS Brodie, SC Pandey, JL Cadet… - Journal of Personalized …, 2022 - mdpi.com
Excessive alcohol intake, eg, binge drinking, is a serious and mounting public health
problem in the United States and throughout the world. Hence the need for novel insights …

[HTML][HTML] Summary document research on RDS anti-addiction modeling: annotated bibliography

K Blum, D Baron, T McLaughlin… - Journal of addiction …, 2024 - ncbi.nlm.nih.gov
Annotated bibliography of genetic addiction risk severity (GARS) publications, pro-dopamine
regulation in nutraceuticals (KB220 nutraceutical variants), and policy documents. Further …

Genetic Addiction risk and psychological profiling analyses for “Preaddiction” Severity Index

K Blum, D Han, A Bowirrat, BW Downs… - Journal of Personalized …, 2022 - mdpi.com
Since 1990, when our laboratory published the association of the DRD2 Taq A1 allele and
severe alcoholism in JAMA, there has been an explosion of genetic candidate association …

The lived experiences of individuals and coping strategies in the context of internet gaming disorder: A qualitative study within higher education setting in Uganda

V Nalwoga, S Kizito, E Kigongo, P Atwine… - Neuropsychiatric …, 2024 - Taylor & Francis
Background Internet Gaming Disorder (IGD), recognized as a mental disorder in both the
Diagnostic and Statistical Manual (DSM-5) and International Classification of Diseases (ICD …

Theorizing the Role of Dopaminergic Polymorphic Risk Alleles with Intermittent Explosive Disorder (IED), Violent/Aggressive Behavior and Addiction: Justification of …

EJ Modestino, K Blum, CA Dennen, BW Downs… - Journal of personalized …, 2022 - mdpi.com
Scientific studies have provided evidence that there is a relationship between violent and
aggressive behaviors and addictions. Genes involved with the reward system, specifically …

The Future is Now for Precision Genomic Addiction Medicine as a Frontline Modality for Inducing “Dopamine Homeostasis” in Reward Deficiency Syndrome (RDS)

ED Gilley, A Bowirrat, A Gupta… - Current …, 2024 - ingentaconnect.com
In this genomic era of addiction medicine, ideal treatment planning begins with genetic
screening to determine neurogenetic antecedents of the Reward Deficiency Syndrome …

Future newborns with opioid-induced Neonatal Abstinence Syndrome (NAS) could be assessed with the Genetic Addiction Risk Severity (GARS) test and potentially …

M Ceccanti, K Blum, A Bowirrat, CA Dennen… - Journal of Personalized …, 2022 - mdpi.com
In this nonsystematic review and opinion, including articles primarily selected from PubMed,
we examine the pharmacological and nonpharmacological treatments of neonatal …