[HTML][HTML] Biomarkers of aging in frailty and age-associated disorders: State of the art and future perspective
S Salvioli, MS Basile, L Bencivenga, S Carrino… - Ageing Research …, 2023 - Elsevier
According to the Geroscience concept that organismal aging and age-associated diseases
share the same basic molecular mechanisms, the identification of biomarkers of age that can …
share the same basic molecular mechanisms, the identification of biomarkers of age that can …
Alzheimer's disorder: epigenetic connection and associated risk factors
The gene based therapeutics and drug targets have shown incredible and appreciable
advances in alleviating human sufferings and complexities. Epigenetics simply means …
advances in alleviating human sufferings and complexities. Epigenetics simply means …
Blood DNA methylation and COVID-19 outcomes
J Balnis, A Madrid, KJ Hogan, LA Drake, HC Chieng… - Clinical …, 2021 - Springer
Background There are no prior reports that compare differentially methylated regions of DNA
in blood samples from COVID-19 patients to samples collected before the SARS-CoV-2 …
in blood samples from COVID-19 patients to samples collected before the SARS-CoV-2 …
Machine learning to detect Alzheimer's disease from circulating non-coding RNAs
Blood-borne small non-coding (sncRNAs) are among the prominent candidates for blood-
based diagnostic tests. Often, high-throughput approaches are applied to discover …
based diagnostic tests. Often, high-throughput approaches are applied to discover …
Role of epigenetics in Alzheimer's disease pathogenesis
A Stoccoro, F Coppedè - Neurodegenerative disease management, 2018 - Taylor & Francis
Advances in molecular biology technologies have allowed uncovering the role of epigenetic
regulation in several complex diseases, such as cancer and neurodegenerative disorders …
regulation in several complex diseases, such as cancer and neurodegenerative disorders …
Functional foods: an approach to modulate molecular mechanisms of Alzheimer's disease
A Atlante, G Amadoro, A Bobba, V Latina - Cells, 2020 - mdpi.com
A new epoch is emerging with intense research on nutraceuticals, ie,“food or food product
that provides medical or health benefits including the prevention and treatment of diseases” …
that provides medical or health benefits including the prevention and treatment of diseases” …
Cross-tissue analysis of blood and brain epigenome-wide association studies in Alzheimer's disease
T C. Silva, JI Young, L Zhang, L Gomez… - Nature …, 2022 - nature.com
To better understand DNA methylation in Alzheimer's disease (AD) from both mechanistic
and biomarker perspectives, we performed an epigenome-wide meta-analysis of blood DNA …
and biomarker perspectives, we performed an epigenome-wide meta-analysis of blood DNA …
Harnessing peripheral DNA methylation differences in the Alzheimer's Disease Neuroimaging Initiative (ADNI) to reveal novel biomarkers of disease
A Vasanthakumar, JW Davis, K Idler, JF Waring… - Clinical …, 2020 - Springer
Background Alzheimer's disease (AD) is a chronic progressive neurodegenerative disease
impacting an estimated 44 million adults worldwide. The causal pathology of AD …
impacting an estimated 44 million adults worldwide. The causal pathology of AD …
Phenotypic heterogeneity in dementia: a challenge for epidemiology and biomarker studies
Dementia can result from a number of distinct diseases with differing etiology and
pathophysiology. Even within the same disease, there is considerable phenotypic …
pathophysiology. Even within the same disease, there is considerable phenotypic …
Micro RNA as a potential blood-based epigenetic biomarker for Alzheimer's disease
PD Fransquet, J Ryan - Clinical Biochemistry, 2018 - Elsevier
As the prevalence of Alzheimer's disease (AD) increases, the search for a definitive, easy to
access diagnostic biomarker has become increasingly important. Micro RNA (miRNA) …
access diagnostic biomarker has become increasingly important. Micro RNA (miRNA) …