Monoclonal B-cell lymphocytosis, monoclonal gammopathy of undetermined significance,
and T-cell clones of uncertain significance are three premalignant conditions characterised …

Precursor diseases of multiple myeloma (MM), the most prevalent plasma cell dyscrasia,
include monoclonal (M) gammopathy of undetermined significance (MGUS) and smoldering …

Background Smoldering myeloma (SMM) is an asymptomatic precursor condition to multiple
myeloma (MM) with a variable risk of progression. The management of high-risk SMM (HR …

Multiple myeloma is preceded by monoclonal gammopathy of undetermined significance
(MGUS). Serum markers are currently used to stratify MGUS patients into clinical risk groups …

Multiple myeloma (MM) is a clonal bone marrow disorder of plasma cells. MM is preceded
by the precursor conditions monoclonal gammopathy of undetermined significance (MGUS) …

Multiple Myeloma (MM) is a plasma cell cancer with high mortality and morbidity rates. Its
incidence rate has increased by 143% since 1975. Adipokines, cytokines, chemokines, and …

While the current approach to precursor hematologic conditions is to “watch and wait,” this
may change with the development of therapies that are safe and extend survival or delay the …

Purpose: Early intervention for high-risk smoldering multiple myeloma (HR-SMM) achieves
deep and prolonged responses. It is unclear if beneficial outcomes are due to the treatment …

Early intervention for High-Risk Smoldering Multiple Myeloma (HR-SMM) achieves deeper
and more prolonged responses compared to Newly Diagnosed (ND) MM. It is unclear if …

Smoldering multiple myeloma (MM) is an asymptomatic clonal plasma cell condition
considered as a premalignant entity that may evolve over time to symptomatic MM. Based on …