HUS and atypical HUS

TS Jokiranta - Blood, The Journal of the American Society of …, 2017 - ashpublications.org
Hemolytic uremic syndrome (HUS) is a thrombotic microangiopathy characterized by
intravascular hemolysis, thrombocytopenia, and acute kidney failure. HUS is usually …

Atypical hemolytic–uremic syndrome

M Noris, G Remuzzi - New England Journal of Medicine, 2009 - Mass Medical Soc
The hemolytic–uremic syndrome, which is characterized by nonimmune hemolytic anemia,
thrombocytopenia, and renal impairment, occurs most frequently in young children. Most …

Horror Autoinflammaticus: The Molecular Pathophysiology of Autoinflammatory Disease

SL Masters, A Simon, I Aksentijevich… - Annual review of …, 2009 - annualreviews.org
The autoinflammatory diseases are characterized by seemingly unprovoked episodes of
inflammation, without high-titer autoantibodies or antigen-specific T cells. The concept was …

STEC-HUS, atypical HUS and TTP are all diseases of complement activation

M Noris, F Mescia, G Remuzzi - Nature Reviews Nephrology, 2012 - nature.com
Haemolytic uraemic syndrome (HUS) and thrombotic thrombocytopaenic purpura (TTP) are
diseases characterized by microvascular thrombosis, with consequent thrombocytopaenia …

[HTML][HTML] The complement system: history, pathways, cascade and inhibitors

P Nesargikar, B Spiller, R Chavez - European Journal of …, 2012 - akjournals.com
Since its discovery in the 19th century, the complement system has developed into a
clinically significant entity. The complement system has been implicated in a variety of …

Combined complement gene mutations in atypical hemolytic uremic syndrome influence clinical phenotype

E Bresin, E Rurali, J Caprioli… - Journal of the …, 2013 - journals.lww.com
Several abnormalities in complement genes reportedly contribute to atypical hemolytic
uremic syndrome (aHUS), but incomplete penetrance suggests that additional factors are …

[HTML][HTML] Atypical hemolytic uremic syndrome

D Kavanagh, TH Goodship, A Richards - Seminars in nephrology, 2013 - Elsevier
Hemolytic uremic syndrome (HUS) is a triad of microangiopathic hemolytic anemia,
thrombocytopenia, and acute renal failure. The atypical form of HUS is a disease …

[HTML][HTML] Atypical hemolytic uremic syndrome

C Loirat, V Frémeaux-Bacchi - Orphanet journal of rare diseases, 2011 - Springer
Hemolytic uremic syndrome (HUS) is defined by the triad of mechanical hemolytic anemia,
thrombocytopenia and renal impairment. Atypical HUS (aHUS) defines non Shiga-toxin …

[HTML][HTML] An update for atypical haemolytic uraemic syndrome: diagnosis and treatment. A consensus document

JM Campistol, M Arias, G Ariceta, M Blasco… - Nefrología (English …, 2015 - Elsevier
Haemolytic uraemic syndrome (HUS) is a clinical entity defined as the triad of nonimmune
haemolytic anaemia, thrombocytopenia, and acute renal failure, in which the underlying …

Genetics of HUS: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome

J Caprioli, M Noris, S Brioschi, G Pianetti, F Castelletti… - Blood, 2006 - ashpublications.org
Hemolytic uremic syndrome (HUS) is a thrombotic microangiopathy with manifestations of
hemolytic anemia, thrombocytopenia, and renal impairment. Genetic studies have shown …