Current management of aortic aneurysms relies exclusively on prophylactic operative repair
of larger aneurysms. Great potential exists for successful medical therapy that halts or …

Objective This review describes ongoing efforts to develop a medical therapy to limit
abdominal aortic aneurysm (AAA) growth. Methods Data from animal model studies, human …

Importance Currently there is no drug therapy for abdominal aortic aneurysm (AAA).
Objective To test the efficacy of the angiotensin receptor blocker telmisartan in slowing AAA …

Abdominal aortic aneurysm (AAA) rupture is estimated to cause 200,000 deaths each year.
Currently, the only treatment for AAA is surgical repair; however, this is only indicated for …

Aortic aneurysm is a permanent focal dilation of the aorta. It is usually an asymptomatic
disease but can lead to sudden death due to aortic rupture. Aortic aneurysm-related …

Background: Abdominal aortic aneurysm (AAA), a progressive segmental abdominal aortic
dilation, is associated with high mortality. AAA is characterized by inflammation, smooth …

Objectives Currently there is no drug therapy for abdominal aortic aneurysm (AAA) and most
previous investigations have focused on imaging rather than clinical outcomes. The aim of …

Abdominal aortic aneurysm (AAA) is a severe vascular disease and a major public health
issue with an unmet medical need for therapy. This disease is featured by a progressive …

Pentagalloyl glucose (PGG) is an elastin-stabilizing polyphenolic compound that has
significant biomedical benefits, such as being a free radical sink, an anti-inflammatory agent …

Studies have shown that angiotensin converting enzyme inhibitors (ACEIs) are superior in
primary and secondary prevention for cardiac mortality and morbidity to angiotensin receptor …