Epigenetic signatures in gastric cancer: current knowledge and future perspectives
F Sogutlu, M Pekerbas, C Biray Avci - Expert Review of Molecular …, 2022 - Taylor & Francis
Introduction Gastric cancer (GC) is the fifth most common malignancy in the world and
accounts for 7.7% of all cancer-related deaths. Early diagnosis of GC is critical in terms of …
accounts for 7.7% of all cancer-related deaths. Early diagnosis of GC is critical in terms of …
Management of triple-negative breast cancer by natural compounds through different mechanistic pathways
Triple-negative breast cancer (TNBC) is the most severe form of breast cancer,
characterized by the loss of estrogen, progesterone, and human epidermal growth factor …
characterized by the loss of estrogen, progesterone, and human epidermal growth factor …
DNMT3B overexpression downregulates genes with CpG islands, common motifs, and transcription factor binding sites that interact with DNMT3B
J Loaeza-Loaeza, AJ Cerecedo-Castillo… - Scientific Reports, 2022 - nature.com
DNA methylation is a key epigenetic modification to regulate gene expression in mammalian
cells. Abnormal DNA methylation in gene promoters is common across human cancer types …
cells. Abnormal DNA methylation in gene promoters is common across human cancer types …
Integrated Analysis of Multiomics Data Identified Molecular Subtypes and Oxidative Stress‐Related Prognostic Biomarkers in Glioblastoma Multiforme
Y Ma, Z Xi - Oxidative Medicine and Cellular Longevity, 2022 - Wiley Online Library
Glioblastoma multiforme (GBM) is a glioma in IV stage, which is one of the most common
primary malignant brain tumors in adults. GBM has the characters of high invasiveness, high …
primary malignant brain tumors in adults. GBM has the characters of high invasiveness, high …
[HTML][HTML] Methods in DNA methylation array dataset analysis: A review
K Sahoo, V Sundararajan - Computational and Structural Biotechnology …, 2024 - Elsevier
Understanding the intricate relationships between gene expression levels and epigenetic
modifications in a genome is crucial to comprehending the pathogenic mechanisms of many …
modifications in a genome is crucial to comprehending the pathogenic mechanisms of many …
Role of HOX genes in cancer progression and their therapeutical aspects
HOX genes constitute a family of evolutionarily conserved transcription factors that play
pivotal roles in embryonic development, tissue patterning, and cell differentiation. These …
pivotal roles in embryonic development, tissue patterning, and cell differentiation. These …
家蚕DNA 甲基转移酶功能预测及其在BmNPV 感染下的表达特征
张一川, 张永红, 邵榆岚, 白兴荣 - 南方农业学报, 2022 - nfnyxb.xml-journal.net
[目的] 明确家蚕DNA 甲基转移酶基因(BmDNMT) 生物信息学基本特征及其在家蚕核型多角体
病毒(BmNPV) 感染前后的表达情况, 揭示DNA 甲基化在家蚕抗病毒免疫方面的作用机制 …
病毒(BmNPV) 感染前后的表达情况, 揭示DNA 甲基化在家蚕抗病毒免疫方面的作用机制 …
Epigenetic Regulation of Mammalian Cardiomyocyte Development
The heart is the first organ formed during mammalian development and functions to
distribute nutrients and oxygen to other parts of the developing embryo. Cardiomyocytes are …
distribute nutrients and oxygen to other parts of the developing embryo. Cardiomyocytes are …
Dnmt3bas coordinates transcriptional induction and alternative exon inclusion to promote catalytically active Dnmt3b expression
Embryonic expression of DNMT3B is critical for establishing de novo DNA methylation. This
study uncovers the mechanism through which the promoter-associated long non-coding …
study uncovers the mechanism through which the promoter-associated long non-coding …
前列腺癌相關之人類基因甲基轉移酶突變體的結構和生化研究
黃薰禾 - 2023 - tdr.lib.ntu.edu.tw
哺乳動物的DNA 甲基化是一種在調節各種細胞事件中, 發揮關鍵作用的表觀遺傳修飾機制.
甲基化失調與多種人類疾病, 包括癌症有關. 在哺乳動物中, DNA 甲基化是由三種DNA …
甲基化失調與多種人類疾病, 包括癌症有關. 在哺乳動物中, DNA 甲基化是由三種DNA …